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General Information
Symbol
Dmel\spis3547
Species
D. melanogaster
Name
FlyBase ID
FBal0009312
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
s3547
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{lacW}spis3547
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies heterozygous for spis3547 have normal cardiac function.

Heterozygotes show a direct effect on the shape of the wing, having an effect in the anterior region, but no effect in the posterior region.

spis3547 embryos have severe defects in migration of the ganglionic branch trachea during stage 16, with many branches crossing the midline. The ventral nerve cord is also defective in these embryos, with longitudinal fascicles collapsed onto the midline.

Homozygous embryos exhibit deletion of median parts of all denticle belts.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

spis3547/spi[+] is an enhancer of visible | dominant phenotype of EgfrE1

NOT Enhancer of
Statement
Reference
Suppressor of
Statement
Reference

spis3547 is a suppressor of visible phenotype of RetMEN2B.GMR

spis3547 is a suppressor of visible phenotype of RetMEN2A.GMR

NOT Suppressor of
Statement
Reference
Phenotype Manifest In
Enhancer of
Statement
Reference

spis3547/spi[+] is an enhancer of eye phenotype of EgfrE1

NOT Enhancer of
Statement
Reference
Suppressor of
Statement
Reference

spis3547 is a suppressor of eye phenotype of RetMEN2B.GMR

spis3547 is a suppressor of eye phenotype of RetMEN2A.GMR

NOT Suppressor of
Statement
Reference

spis3547 is a non-suppressor of eye phenotype of CanBGMR.PS, Pp2B-14Dact.GMR

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer

M. Scott.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (17)