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General Information
Symbol
Dmel\Pp2B-14Dact.GMR
Species
D. melanogaster
Name
FlyBase ID
FBal0137392
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

GMR regulatory sequences drive expression of a mutated form of Pp2B-14D that has a stop codon introduced at residue 456.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies carrying one copy of Pp2B-14Dact.GMR have a mild rough eye phenotype. Ommatidial morphology and organisation is aberrant. No effect on cell death or cell proliferation is seen.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

CanBGMR.PS, Pp2B-14Dact.GMR has visible phenotype, enhanceable by Ras85De1B/Ras85D[+]

NOT Enhanced by
Statement
Reference

CanBGMR.PS, Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by spi1

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by Egfrf2

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by Ras85De1B

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by Ras85De2F

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by Rho172O

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by Rho1k07903

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by Sose2H

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by Sose46

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by aop1

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by aopyan-XE18

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by dos1.46

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by dos2.42

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by drke0A/drke0A

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by drkk02401

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by ksr1080

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by ksrS-627

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by phyl2245

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by phylS-221

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by pnt3680Δ21

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by pnt7825Δ77

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by rlS-135

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by rlXS-324

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by sina3

Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by sina4

CanBGMR.PS, Pp2B-14Dact.GMR has visible phenotype, non-enhanceable by aop1

Suppressed by
Statement
Reference

Pp2B-14Dact.GMR has visible phenotype, suppressible by Df(1)JC70/+

Pp2B-14Dact.GMR has visible phenotype, suppressible by Gap1PB

Pp2B-14Dact.GMR has visible phenotype, suppressible by sl1

Pp2B-14Dact.GMR has visible phenotype, suppressible by sl2

Pp2B-14Dact.GMR has visible phenotype, suppressible by sl3

Pp2B-14Dact.GMR has visible phenotype, suppressible by styΔ5

Pp2B-14Dact.GMR has visible phenotype, suppressible by sty518

Pp2B-14Dact.GMR has visible phenotype, suppressible by gl60j/gl[+]

NOT suppressed by
Statement
Reference

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by Egfrf2

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by Sose2H

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by Sose46

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by aop1

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by aopyan-XE18

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by dos1.46

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by Ras85De1B

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by dos2.42

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by drke0A/drke0A

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by drkk02401

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by ksr1080

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by ksrS-627

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by phyl2245

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by phylS-221

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by pnt3680Δ21

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by pnt7825Δ77

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by Ras85De2F

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by rlS-135

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by rlXS-324

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by sina3

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by sina4

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by Rho172O

CanBGMR.PS, Pp2B-14Dact.GMR has visible phenotype, non-suppressible by aop1

Pp2B-14Dact.GMR has visible phenotype, non-suppressible by Rho1k07903

CanBGMR.PS, Pp2B-14Dact.GMR has visible phenotype, non-suppressible by Raf11

CanBGMR.PS, Pp2B-14Dact.GMR has visible phenotype, non-suppressible by Raf12

CanBGMR.PS, Pp2B-14Dact.GMR has visible phenotype, non-suppressible by sina3

CanBGMR.PS, Pp2B-14Dact.GMR has visible phenotype, non-suppressible by sina4

CanBGMR.PS, Pp2B-14Dact.GMR has visible phenotype, non-suppressible by spi1

Phenotype Manifest In
Enhanced by
Statement
Reference

Pp2B-14Dact.GMR has eye phenotype, enhanceable by CE3-3466

Pp2B-14Dact.GMR has eye phenotype, enhanceable by styGMR.PS

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, enhanceable by Ras85De1B/Ras85D[+]

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, enhanceable by pnt3680Δ21/pnt[+]

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, enhanceable by pnt[+]/pnt7825Δ77

NOT Enhanced by
Statement
Reference

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by dos1.46

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by dos2.42

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by ksr1080

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by ksrS-627

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by Raf11

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by Raf12

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by phyl2245

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by rlS-135

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by rlXS-324

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by sina3

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by sina4

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by spi1

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by spis3547

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by Egfrf2

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by Ras85De1B

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by Ras85De2F

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by Rho172O

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by Rho1k07903

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by Sose2H

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by Sose46

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by aop1

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by aopyan-XE18

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by dos1.46

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by dos2.42

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by drke0A/drke0A

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by drkk02401

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by ksr1080

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by ksrS-627

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by phyl2245

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by phylS-221

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by pkunspecified

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by pnt3680Δ21

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by pnt7825Δ77

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by rlS-135

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by rlXS-324

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by sina3

Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by sina4

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by CblF165

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by Rho172O

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by Sose2H

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by Sose46

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by aop1

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-enhanceable by aos05845

Suppressed by
Statement
Reference

Pp2B-14Dact.GMR has eye phenotype, suppressible by CS3-1465

Pp2B-14Dact.GMR has eye phenotype, suppressible by CanB2180

Pp2B-14Dact.GMR has eye phenotype, suppressible by CanB287

Pp2B-14Dact.GMR has eye phenotype, suppressible by Df(1)JC70/+

Pp2B-14Dact.GMR has eye phenotype, suppressible by RasGAP1B1

Pp2B-14Dact.GMR has eye phenotype, suppressible by Gap1PB

Pp2B-14Dact.GMR has eye phenotype, suppressible by sl1

Pp2B-14Dact.GMR has eye phenotype, suppressible by sl2

Pp2B-14Dact.GMR has eye phenotype, suppressible by sl3

Pp2B-14Dact.GMR has eye phenotype, suppressible by styΔ5

Pp2B-14Dact.GMR has eye phenotype, suppressible by styΔ64

Pp2B-14Dact.GMR has eye phenotype, suppressible by sty518

Pp2B-14Dact.GMR has eye phenotype, suppressible by gl60j/gl[+]

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, suppressible by sl1

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, suppressible by sl2

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, suppressible by sl3

NOT suppressed by
Statement
Reference

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by Egfrf2

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by Sose2H

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by Sose46

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by aop1

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by aopyan-XE18

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by dos1.46

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by dos2.42

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by drke0A/drke0A

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by drkk02401

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by ksr1080

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by ksrS-627

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by Ras85De1B

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by phyl2245

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by phylS-221

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by pkunspecified

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by pnt3680Δ21

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by pnt7825Δ77

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by rlS-135

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by rlXS-324

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by sina3

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by sina4

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by Ras85De2F

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by CblF165

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by Rho172O

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by Sose2H

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by Sose46

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by aop1

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by aos05845

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by dos1.46

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by Rho172O

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by dos2.42

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by drkk02401

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by ksr1080

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by ksrS-627

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by Raf11

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by Raf12

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by phyl2245

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by phylS-221

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by rlS-135

Pp2B-14Dact.GMR has eye phenotype, non-suppressible by Rho1k07903

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by rlXS-324

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by sina3

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by sina4

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by spi1

CanBGMR.PS, Pp2B-14Dact.GMR has eye phenotype, non-suppressible by spis3547

Additional Comments
Genetic Interactions
Statement
Reference

The rough eye phenotype of Pp2B-14Dact.GMR flies is strongly suppressed by one copy of gl60j or Df(1)JC70. The severity of the rough eye phenotype of Pp2B-14Dact.GMR flies is increased by CanBGMR.PS. Df(3L)CS3-3-154 suppresses the rough eye phenotype of Pp2B-14Dact.GMR, CanBGMR.PS flies. EgfrE1/+ flies carrying Pp2B-14Dact.GMR and CanBGMR.PS have a rough eye phenotype similar to that caused by Pp2B-14Dact.GMR and CanBGMR.PS in an Egfr+ background.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Pp2B-14Dact.GMR
Name Synonyms
Secondary FlyBase IDs
    References (1)