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General Information
Symbol
Dmel\crbj1B5
Species
D. melanogaster
Name
FlyBase ID
FBal0086975
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{lacW}crbj1B5
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

crbj1B5/Df(3R)P3-4-7 transheterozygotes are lethal.

Stage 17 crbj1B5 mutant embryos show defects in the transition from luminal liquid-clearance to air-filled airways. Tube size defects and defective airway protein clearance are also seen. No air-filling defects are observed in crbj1B5 heterozygotes.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

crbj1B5/crb[+] is an enhancer of visible phenotype of RetMEN2B.GMR

crbj1B5/crb[+] is an enhancer of visible phenotype of RetMEN2A.GMR

crbj1B5/crb[+] is an enhancer of visible phenotype of RetGMR.PR

NOT Enhancer of
Statement
Reference

crbj1B5/crb[+] is a non-enhancer of visible | dominant phenotype of EgfrE1

Suppressor of
Statement
Reference

crbj1B5/crb[+] is a suppressor | partially of visible | heat sensitive phenotype of Dcr-2UAS.cDa, EogtGD5084, Scer\GAL4en.PU

crbj1B5 is a suppressor of visible phenotype of upd1GMR.PB

NOT Suppressor of
Statement
Reference

crbj1B5/crb[+] is a non-suppressor of visible | dominant phenotype of EgfrE1

Phenotype Manifest In
Enhancer of
Statement
Reference

crbj1B5/crb[+] is an enhancer of eye phenotype of RetMEN2B.GMR

crbj1B5/crb[+] is an enhancer of eye phenotype of RetMEN2A.GMR

crbj1B5/crb[+] is an enhancer of eye phenotype of RetGMR.PR

NOT Enhancer of
Statement
Reference

crbj1B5/crb[+] is a non-enhancer of eye phenotype of EgfrE1

Suppressor of
Statement
Reference

crbj1B5 is a suppressor of eye phenotype of upd1GMR.PB

NOT Suppressor of
Statement
Reference

crbj1B5/crb[+] is a non-suppressor of eye phenotype of EgfrE1

Other
Additional Comments
Genetic Interactions
Statement
Reference

The wing blistering phenotype seen in the posterior compartment of wings in flies expressing EogtGD5084 under the control of Scer\GAL4en.PU in the presence of Dcr-2Scer\UAS.cDa is weakly but significantly suppressed if the flies are also heterozygous for crbj1B5.

Transheterozygous wusG0162 crbj1B5 stage 17 embryos show defects in in the transition from luminal liquid-clearance to air-filled airways.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially complements
Fails to complement
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
Comments
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (8)