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General Information
Symbol
Dmel\Ser+r83k
Species
D. melanogaster
Name
FlyBase ID
FBal0042741
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The combination of the SerBd-3 and Ser+r83k alleles in trans results in the development of a vestigial wing.

SerBd-3/Ser+r83k transheterozygotes are pupal lethal.

Heterozygotes with SerBd-3 die as pharate adults with abnormalities in the leg such as fusion of the femur and tibial segments and loss of the wing blade. Homozygotes and hemizygotes are viable.

Loss of the dominant wing nicking phenotype. SerBd-3 Ser+r83k combination is lethal, flies die as pupae and when dissected from the pupal case they exhibit eye roughening, lack of wing blade and haltere material and fusion of the first and second tarsal segment of all six legs.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference

SerBd-3/Ser+r83k has visible phenotype, suppressible | partially by N414

SerBd-3/Ser+r83k has visible phenotype, suppressible | partially by Nl93

SerBd-3/Ser+r83k has visible phenotype, suppressible | partially by Nl1N-B

Phenotype Manifest In
Suppressed by
Statement
Reference

SerBd-3/Ser+r83k has wing phenotype, suppressible | partially by N414

SerBd-3/Ser+r83k has wing phenotype, suppressible | partially by Nl93

SerBd-3/Ser+r83k has wing phenotype, suppressible | partially by Nl1N-B

Additional Comments
Genetic Interactions
Statement
Reference

The addition of Df(1)N-81k1 or NAx-59d has no effect on the SerBd-3/Ser+r83k wing phenotype. The addition of N414 or Nl93 partially suppresses the SerBd-3/Ser+r83k wing phenotype.

In combination with Nl93 or Df(1)N-54l9, SerBd-3/Ser+r83k escapers exhibit phenotypically normal eyes and legs but lack halteres and had wing blades one half normal size.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Ser+r83k
Name Synonyms
Secondary FlyBase IDs
    References (6)