FlyBase Allele Report: Dmel\phyl[GMR.PC]

General Information

Symbol

Dmel\phyl^GMR.PC

Species

D. melanogaster

Name

glass multimer reporter construct of Chang

FlyBase ID

FBal0044268

Feature type

allele

Associated gene

Dmel\phyl

Associated Insertion(s)

Carried in Construct

P{GMR-phyl}

Also Known As

GMR-phyl

Key Links

Transgenic product class

wild_type

(Chang et al., 1995)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Chang et al., 1995)

Mutagen

in vitro construct

(Chang et al., 1995)

Progenitor genotype

Carried in construct

P{GMR-phyl}

Cytology

Description

GMR regulatory sequences drive expression of phyl.

(Chang et al., 1995)

Allele components

Component

Use(s)

Regulatory region(s)

GMR

engineered transcription regulatory region

Encoded product / tool

phyl

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Tang et al., 2001)

visible | dominant

(Tang et al., 1997)

Phenotype Manifest In

eye

(Tang et al., 2001, Tang et al., 1997)

ommatidium

(Tang et al., 2001)

Detailed Description

Statement

Reference

Flies carrying phyl^GMR.PC have a rough eye phenotype.

(Tang et al., 2001)

Flies carrying phyl^GMR.PC have rough eyes.

(Tang et al., 1997)

Pigment cell precursors adopt neuronal characteristics.

(Chang et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

phyl^GMR.PC has visible phenotype, suppressible by lilli^XS407

(Tang et al., 2001)

phyl^GMR.PC has visible phenotype, suppressible by lilli^s35

(Tang et al., 2001)

phyl^GMR.PC has visible phenotype, suppressible by lilli^XS575

(Tang et al., 2001)

phyl^GMR.PC has visible | dominant phenotype, suppressible by ttk^{88.GMR.Tag:MYC}

(Tang et al., 1997)

Phenotype Manifest In

Suppressed by

Statement

Reference

phyl^GMR.PC has ommatidium phenotype, suppressible by lilli^XS407

(Tang et al., 2001)

phyl^GMR.PC has ommatidium phenotype, suppressible by lilli^XS575

(Tang et al., 2001)

phyl^GMR.PC has ommatidium phenotype, suppressible by lilli^s35

(Tang et al., 2001)

phyl^GMR.PC has eye phenotype, suppressible by ttk^{88.GMR.Tag:MYC}

(Tang et al., 1997)

phyl^GMR.PC has photoreceptor neuron phenotype, suppressible by ttk^{88.GMR.Tag:MYC}

(Tang et al., 1997)

phyl^GMR.PC has eye phenotype, suppressible by sina³/sina²

(Tang et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

Flies carrying both phyl^GMR.PC and ttk^{88.GMR.T:Hsap\MYC} have nearly wild-type eyes, with most of the ommatidia having close to the normal number of photoreceptor cells. The phyl^GMR.PC eye phenotype is completely suppressed in a sina²/sina³ background; the eyes are normal, except for the lack of R7 photoreceptor cells due to the absence of sina function. sina²/sina³ flies carrying both phyl^GMR.PC and ttk^{88.GMR.T:Hsap\MYC} have very disrupted eyes, similar to those of flies carrying ttk^{88.GMR.T:Hsap\MYC} alone.

(Tang et al., 1997)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

5772

P{GMR-phyl}l(3)HC1¹/TM3, Sb¹

Notes on Origin

Discoverer

Comments

The GMR functions in all retinal precursor cells behind the furrow.

(Chang et al., 1995)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

phyl^GMR.PC

phyl^ninaE.GMR

Name Synonyms

glass multimer reporter construct of Chang

Secondary FlyBase IDs

References (5)

Report Sections

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