FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ocγa1
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General Information
Symbol
Dmel\ocγa1
Species
D. melanogaster
Name
FlyBase ID
FBal0046212
Feature type
allele
Associated gene
Dmel\oc
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
gamma ray
(Spradling et al., 1994)
Progenitor genotype
Caused by aberration
T(1;2)ocγ1
Cytology
Description

Associated with a translocation with a breakpoint in 8A1.

(Wieschaus et al., 1992)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Animals expressing ocScer\UAS.cBa under the control of Scer\GAL4oc.2 in a ocγa1 mutant background die as pharate adults inside the pupal case. All the animals that survive to the pharate adult stage are females.

      (Blanco et al., 2009)

      Homozygotes exhibit loss of both ocellar structures and frons cuticle, no effect on the lateral orbital region.

      (Royet and Finkelstein, 1996)

      Defects in formation of the protocerebral bridge.

      (Hirth et al., 1995)

      In hemizygotes ocelli and associated bristles are deleted, there are no remaining macrochaetae in this region. Frons cuticle is also deleted. Phenotypic series from the strongest to weakest oc allele: ocdb/ocdb > oc1/oc+ > ocγa1/oc+ > oc2/oc+ > oc1/oc1 > ocγa1/ocγa1 > oc2/oc1 > oc2/ocγa1.

      (Royet and Finkelstein, 1995)

      Adult males hemizygous for ocγa1 have head defects. oc1/ocγa1 transheterozygotes also have head defects. The ocelli and much of the adjacent cuticle is missing. The frons region lacks its typical ridged morphology and has ectopic bristles. oc1/ocγa1 transheterozygotes also variably lack parovaria.

      (Wieschaus et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ocγa1
      (Blanco et al., 2010, Blanco et al., 2009)
      ocγα1
      (Carr et al., 2005)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)