FlyBase Allele Report: Dmel\aop[pok-x8]

General Information

Symbol

Dmel\aop^pok-x8

Species

D. melanogaster

Name

FlyBase ID

FBal0049303

Feature type

allele

Associated gene

Dmel\aop

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Rogge et al., 1995)

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Rogge et al., 1995)

partially lethal - majority die (with aop¹)

(Rogge et al., 1995)

partially lethal - majority die (with aop²)

(Rogge et al., 1995)

partially lethal - majority die (with aop^e2d)

(Rogge et al., 1995)

partially lethal - majority die (with Df(2L)dp-79b)

(Rogge et al., 1995)

viable

(Rogge et al., 1995)

visible (with aop^yan-1)

(Rogge et al., 1995)

visible | recessive

(Rogge et al., 1995)

Phenotype Manifest In

ommatidium

(Rogge et al., 1995)

ommatidium (with aop¹)

(Rogge et al., 1995)

ommatidium (with aop²)

(Rogge et al., 1995)

ommatidium (with aop^e2d)

(Rogge et al., 1995)

ommatidium (with aop^yan-1)

(Rogge et al., 1995)

ommatidium (with Df(2L)dp-79b)

(Rogge et al., 1995)

photoreceptor cell R7 | ectopic

(Rogge et al., 1995)

photoreceptor cell R7 | ectopic (with aop¹)

(Rogge et al., 1995)

photoreceptor cell R7 | ectopic (with aop²)

(Rogge et al., 1995)

photoreceptor cell R7 | ectopic (with aop^e2d)

(Rogge et al., 1995)

photoreceptor cell R7 | ectopic (with aop^yan-1)

(Rogge et al., 1995)

photoreceptor cell R7 | ectopic (with Df(2L)dp-79b)

(Rogge et al., 1995)

pigment cell (with aop¹)

(Rogge et al., 1995)

pigment cell (with aop²)

(Rogge et al., 1995)

pigment cell (with aop^e2d)

(Rogge et al., 1995)

pigment cell (with Df(2L)dp-79b)

(Rogge et al., 1995)

Detailed Description

Statement

Reference

Homozygotes and transheterozygotes with aop^yan-1 exhibit small rough eyes due to ectopic R7 cells. Transheterozygotes with aop^e2d, Df(2L)dp-79b, aop¹ or aop² are semi-lethal and the adult escapers have small rough eyes due to fusion of ommatidia, loss of the regular pigment cell array and ectopic R7 cells.

(Rogge et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

aop^pok-x8 has visible phenotype, enhanceable by Dp(1;2)51b

(Rogge et al., 1995)

Suppressed by

Statement

Reference

aop^pok-x8 has visible phenotype, suppressible by N^55e11

(Rogge et al., 1995)

Phenotype Manifest In

Enhanced by

Statement

Reference

aop^pok-x8 has ommatidium phenotype, enhanceable by Dp(1;2)51b

(Rogge et al., 1995)

Suppressed by

Statement

Reference

aop^pok-x8 has ommatidium phenotype, suppressible by N^55e11

(Rogge et al., 1995)

Suppressor of

Statement

Reference

aop^pok-x8 is a suppressor of photoreceptor cell R7 phenotype of Sos^JC2, sev⁶

(Rogge et al., 1995)

Additional Comments

Genetic Interactions

Statement

Reference

sev⁶/sev⁺;Sos^JC2/aop^pok-x8 mutants exhibit an increase in the number of R7 cells compared to sev⁶/Sos^JC2 mutants with two functional aop copies. Transheterozygotes with Dp(1;2)51b exhibit enhancement of the rough eye phenotype and transheterozygotes with N^55e11 exhibit suppression of the mutant eye phenotype.

(Rogge et al., 1995)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

aop^yan-1

(Rogge et al., 1995)

Partially complements

aop²

(Rogge et al., 1995)

aop¹

(Rogge et al., 1995)

aop^e2d

(Rogge et al., 1995)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

aop^pok-x8

yan^pok-x8

(Rogge et al., 1995)

yan^pokx8

(Flores et al., 2000)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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