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General Information
Symbol
Dmel\aope2d
Species
D. melanogaster
Name
FlyBase ID
FBal0049301
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
yane2D
Key Links
Mutagen
    Nature of the Allele
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    aopyan-1/aope2d eye discs show chirality defects in ommatidial clusters.

    Heterozygotes with aoppok-x8 or aopyan-1 are semi-lethal and the adult escapers have small rough eyes due to fusion of ommatidia, loss of the regular pigment cell array and ectopic R7 cells.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Enhancer of
    Statement
    Reference
    Suppressor of
    Statement
    Reference

    aop[+]/aope2d is a suppressor | partially of abnormal planar polarity phenotype of dshhs.sev.B

    Other
    Statement
    Reference
    Phenotype Manifest In
    Enhancer of
    Statement
    Reference

    aop[+]/aope2d is an enhancer of ommatidium phenotype of Scer\GAL4hs.2sev, dgoUAS.cFa

    aop[+]/aope2d is an enhancer of ommatidium phenotype of EgfrE1

    NOT Enhancer of
    Statement
    Reference

    aop[+]/aope2d is a non-enhancer of wing hair phenotype of Scer\GAL4hs.2sev, dgoUAS.cFa

    Suppressor of
    Statement
    Reference

    aop[+]/aope2d is a suppressor | partially of ommatidium phenotype of dshhs.sev.B

    aope2d is a suppressor | partially of denticle belt phenotype of Egfrf1

    aope2d is a suppressor of photoreceptor cell R7 phenotype of SosJC2, sev6

    NOT Suppressor of
    Statement
    Reference

    aop[+]/aope2d is a non-suppressor of wing hair phenotype of Scer\GAL4hs.2sev, dgoUAS.cFa

    Other
    Statement
    Reference
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    aope2d/+ enhances the planar cell polarity (PCP) defects in the eye induced by the overexpression of dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev.

    Homozygous kay2 clones in the eye in a aope2d/+ background show ommatidial chirality, rotation and photoreceptor number defects (kay2 single mutant clones do not show tissue polarity defects by themselves).

    One copy of aope2d partially suppresses the formation of symmetrical ommatidia that is seen in animals expressing dshhs.sev.B.

    Loss of wild type ttk promotes the formation of rare ectopic R7 cells.

    Heterozygotes with aoppok-x8 or aopyan-1 are semi-lethal and the adult escapers have small rough eyes due to fusion of ommatidia, loss of the regular pigment cell array and ectopic R7 cells. sev6/sev+;SosJC2/aope2d mutants exhibit an increase in the number of R7 cells compared to sev6/SosJC2 mutants with two functional aop copies.

    sev6/sev+;SosJC2/aope2d mutants exhibit an increase in the number of R7 cells compared to sev6/SosJC2 mutants with two functional aop copies.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (6)
    References (9)