FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Ecol\lacZbyn-apro
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General Information
Symbol
Ecol\lacZbyn-apro
Species
E. coli
Name
FlyBase ID
FBal0056701
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
P{PZ}bynapro
Carried in Construct
Also Known As
Byn-lacZ
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Murakami et al., 1994)
Delta2-3 transposase
(Murakami et al., 1995)
Progenitor genotype
Associated Insertion(s)
P{PZ}bynapro
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage
      embryonic hindgut
      • nucleus
      (Johansen et al., 2003)
      embryonic stage 11 -- 17
      embryonic hindgut
      (Iwaki et al., 2001)
      embryonic stage 14
      embryonic/larval hindgut
      (Hildebrandt et al., 2020)
      embryonic/larval rectum
      (Hildebrandt et al., 2020)
      embryonic small intestine
      (Hildebrandt et al., 2020)
      larval stage
      wing disc | restricted
      (Copf et al., 2003)
      third instar larval stage
      embryonic/larval ileum
      (Hildebrandt et al., 2020)
      embryonic/larval pylorus
      (Hildebrandt et al., 2020)
      embryonic/larval rectum
      (Hildebrandt et al., 2020)
      adult stage
      hindgut
      (Moreno and Morata, 1999)
      adult anterior hindgut
      (Hildebrandt et al., 2020)
      adult pylorus
      (Hildebrandt et al., 2020)
      rectum
      (Hildebrandt et al., 2020)
      in situ
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 14
      anal pad
      (Hildebrandt et al., 2020)
      Additional Information
      Statement
      Reference

      byn reporter and otp expression was compared. Both are expressed throughout the embryonic hindgut at stage 14 but only byn is expressed in the small intestine. Both are expressed in the anal pads and rectum, but only otp has a reduced level of expression in the rectum. Both are expressed in the ileum and rectum in larvae and adults but only byn is expressed in the pylorus.

      (Hildebrandt et al., 2020)
       
      Marker for
      adult hindgut
      (Moreno and Morata, 1999)
      embryonic hindgut
      (Johansen et al., 2003)
      Reflects expression of
      byn
      (Copf et al., 2003, Iwaki et al., 2001, Moreno and Morata, 1999)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Mobilisation of the P{PZ} insertion confirms the insertion is responsible for the mutant phenotype.

      (Murakami et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ecol\lacZbyn-apro
      PY282
      (Murakami et al., 1994)
      lacZbyn-apro
      Name Synonyms
      Secondary FlyBase IDs
        References (8)