FlyBase Allele Report: Dmel\arm[UAS.cSa]

General Information

Symbol

Dmel\arm^UAS.cSa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Sanson

FlyBase ID

FBal0057828

Feature type

allele

Associated gene

Dmel\arm

Associated Insertion(s)

Carried in Construct

P{UAS-arm.S}

Also Known As

UASarm, UAS-arm

Key Links

Transgenic product class

cDNA

(Sanson et al., 1996)

wild_type

(Sanson et al., 1996)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Sanson et al., 1996)

wild_type

(Sanson et al., 1996)

Mutagen

in vitro construct

(Ahmed et al., 1998, Sanson et al., 1996)

Progenitor genotype

Carried in construct

P{UAS-arm.S}

Cytology

Description

UASt regulatory sequences drive expression of an arm cDNA.

(Sanson et al., 1996)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

arm

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^Bx-MS1096

(Lawrence et al., 2000)

visible, with Scer\GAL4^GMR.PF

(Tran et al., 2008)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PF

(Tran et al., 2008)

eye photoreceptor cell, with Scer\GAL4^elav-C155

(Ahmed et al., 1998)

wing margin bristle | ectopic, with Scer\GAL4^en-e16E

(Bauer et al., 2000)

wing sensillum | ectopic, with Scer\GAL4^Bx-MS1096

(Lawrence et al., 2000)

wing vein | ectopic, with Scer\GAL4^Bx-MS1096

(Lawrence et al., 2000)

Detailed Description

Statement

Reference

Flies expressing arm^Scer\UAS.cSa under the control of Scer\GAL4^GMR.PF have a rough eye phenotype.

(Tran et al., 2008)

The expression of arm^Scer\UAS.cSa when driven by Scer\GAL4^en-e16E induces the formation of margin bristles within the posterior wing blade.

(Bauer et al., 2000)

Expression of arm^Scer\UAS.cSa under the control of Scer\GAL4^Bx-MS1096 results in ectopic bristles close to the wing margin and some ectopic vein tissue.

(Lawrence et al., 2000)

The addition of arm^Scer\UAS.cSa (driven by Scer\GAL4^sd-SG29.1) to Df(3R)Dl-FX3/+ flies does not significantly alter the Df(3R)Dl-FX3/+ phenotype.

(Brennan et al., 1999)

Flies expressing arm^Scer\UAS.cSa under the control of Scer\GAL4^elav-C155 show loss of photoreceptor cells. Some ommatidia lose all photoreceptor cells, and most others have a reduction in photoreceptor cell number.

(Ahmed et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, arm^UAS.cSa has visible phenotype, suppressible by trbd^Delta/trbd[+]

(Tran et al., 2008)

Suppressor of

Statement

Reference

arm^UAS.cSa/Scer\GAL4^Bx-MS1096 is a suppressor | partially of visible phenotype of Scer\GAL4^Bx-MS1096, pan^UAS.cWa

(Lawrence et al., 2000)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^en-e16E, arm^UAS.cSa has wing margin bristle | ectopic phenotype, enhanceable by rept³⁵

(Bauer et al., 2000)

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, arm^UAS.cSa has eye phenotype, suppressible by trbd^Delta/trbd[+]

(Tran et al., 2008)

Scer\GAL4^en-e16E, arm^UAS.cSa has wing margin bristle | ectopic phenotype, suppressible by pont^5.1

(Bauer et al., 2000)

Suppressor of

Statement

Reference

arm^UAS.cSa/Scer\GAL4^Bx-MS1096 is a suppressor | partially of wing phenotype of Scer\GAL4^Bx-MS1096, pan^UAS.cWa

(Lawrence et al., 2000)

arm^UAS.cSa/Scer\GAL4^Bx-MS1096 is a suppressor | partially of wing vein | ectopic phenotype of Scer\GAL4^Bx-MS1096, pan^UAS.cWa

(Lawrence et al., 2000)

arm^UAS.cSa/Scer\GAL4^Bx-MS1096 is a suppressor | partially of wing sensillum | ectopic phenotype of Scer\GAL4^Bx-MS1096, pan^UAS.cWa

(Lawrence et al., 2000)

NOT Suppressor of

Statement

Reference

arm^UAS.cSa/Scer\GAL4^Bx-MS1096 is a non-suppressor of wing margin phenotype of Scer\GAL4^Bx-MS1096, pan^UAS.cWa

(Lawrence et al., 2000)

Other

Statement

Reference

N^ECN.UAS, Scer\GAL4^sd-SG29.1, arm^UAS.cSa has sensory mother cell & dorsal mesothoracic disc phenotype

(Brennan et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

trbd^Delta/+ suppresses the rough eye phenotype caused by expression of arm^Scer\UAS.cSa under the control of Scer\GAL4^GMR.PF.

(Tran et al., 2008)

The addition of pont^5.1 suppresses the ectopic wing margin bristle phenotype seen in arm^Scer\UAS.cSa, Scer\GAL4^en-e16E flies, reducing the average number of ectopic bristles seen per wing blade from 11.5 to 5.2. The addition of rept³⁵ enhances the ectopic wing margin bristle phenotype seen in arm^Scer\UAS.cSa, Scer\GAL4^en-e16E flies, increasing the average number of ectopic bristles seen per wing blade from 11.5 to 24.5.

(Bauer et al., 2000)

Co-expression of arm^Scer\UAS.cSa partially suppresses the wing defects caused by expression of pan^Scer\UAS.cWa under the control of Scer\GAL4^Bx-MS1096 : the reduction in wing size, ectopic wing bristle phenotype and wing venation patterns are partially rescued, but the nicking of the wing margin is not suppressed.

(Lawrence et al., 2000)

Ectopic expression of arm^Scer\UAS.cSa rescues the wing defect caused by expression of argos::shg^{i.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^en-e16E to wild type.

(Sanson et al., 1996)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

arm^Scer\UAS.cSa

arm^UAS.cSa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Sanson

(Sanson et al., 1996)

Secondary FlyBase IDs

References (9)

Report Sections

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