FlyBase Allele Report: Dmel\pk[D]

General Information

Symbol

Dmel\pk^D

Species

D. melanogaster

Name

FlyBase ID

FBal0059968

Feature type

allele

Associated gene

Dmel\pk

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

antimorphic allele - genetic evidence

Mutagen

Nature of the Allele

Allele class

antimorphic allele - genetic evidence

(Adler et al., 1997)

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal planar polarity

(Adler et al., 1997)

visible

(Adler et al., 1997)

Phenotype Manifest In

wing hair

(Adler et al., 1997)

Detailed Description

Statement

Reference

Hairs in wing point proximally. In pupal wings prehairs initiate in the vicinity of the proximal most vertex of the cell and grow in a proximal direction, reversing the wild type situation.

(Adler et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

pk^D is an enhancer of abnormal planar polarity | cell non-autonomous | somatic clone phenotype of fz²³

(Adler et al., 2000)

pk^D is an enhancer of abnormal planar polarity | cell non-autonomous phenotype of fz²⁵

(Adler et al., 2000)

Suppressor of

Statement

Reference

pk^D is a suppressor of abnormal planar polarity | somatic clone | cell non-autonomous phenotype of Vang^A3

(Adler et al., 2000)

Other

Statement

Reference

Vang^A3, pk^D has abnormal planar polarity | somatic clone | cell non-autonomous phenotype

(Adler et al., 2000)

Phenotype Manifest In

Enhancer of

Statement

Reference

pk^D is an enhancer of wing | cell non-autonomous | somatic clone phenotype of fz²³

(Adler et al., 2000)

pk^D is an enhancer of wing | cell non-autonomous | somatic clone phenotype of fz²⁵

(Adler et al., 2000)

Suppressor of

Statement

Reference

pk^D is a suppressor of wing | somatic clone | cell non-autonomous phenotype of Vang^A3

(Adler et al., 2000)

Other

Statement

Reference

Vang^A3, pk^D has wing | somatic clone | cell non-autonomous phenotype

(Adler et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

fz²³ clones in homozygous pk^D wings almost always show proximal domineering non-autonomy. That is cells proximal, but not distal to the clone show abnormal polarity. Thus the direction of the domineering non-autonomy is the same as local hair polarity. Homozygous Vang^A3 clones in a pk^D background, all show domineering non-autonomy. The non-autonomy is opposite to the direction of local hair polarity.

(Adler et al., 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

66526

w^*; pk^D

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

pk^D

(Chung et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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