FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\hrg10
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General Information
Symbol
Dmel\hrg10
Species
D. melanogaster
Name
FlyBase ID
FBal0060390
Feature type
allele
Associated gene
Dmel\hrg
Associated Insertion(s)
P{?UAS-RBZ.ftz-F1}hrg10
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Murata et al., 1996)
Progenitor genotype
hrgP1
(Murata et al., 1996)
Associated Insertion(s)
P{?UAS-RBZ.ftz-F1}hrg10
Cytology
Description

Excision of P-element sequences, with 1.2kb of P-element sequences remaining. In addition a region of 40bp surrounding the site of the insertion has been deleted.

(Murata et al., 2001)

Excision of the P-element insertion in hrgP1.

(Murata et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  autosomal recessive intellectual developmental disorder 56
      modeled by Nab2ex3
      (Pak et al., 2011)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      hrg10 has visible phenotype, suppressible by Scer\GAL4C-765/Btau\PapUAS.cMa

      (Murata et al., 2001)
      Enhancer of
      Statement
      Reference

      hrg10/hrg[+] is an enhancer of visible phenotype of Nab2EP3716, Scer\GAL4GMR.PU

      (Pak et al., 2011)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      hrg10 has wing phenotype, suppressible by Scer\GAL4C-765/Btau\PapUAS.cMa

      (Murata et al., 2001)
      Enhancer of
      Statement
      Reference

      hrg10/hrg[+] is an enhancer of eye phenotype of Nab2EP3716, Scer\GAL4GMR.PU

      (Pak et al., 2011)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      hrg10/+ strongly enhances the mutant eye phenotype caused by expression of Nab2EP3716 under the control of Scer\GAL4GMR.PU.

      (Pak et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      hrgP1

      (Murata et al., 1996)
      Rescued by

      hrg10 is rescued by hrgE.UAS/Scer\GAL4C-765

      (Murata et al., 2001)

      hrg10 is rescued by hrg+t6.8

      (Murata et al., 2001)
      Not rescued by

      hrg10 is not rescued by Scer\GAL4C-765/hrgD175A.UAS

      (Murata et al., 2001)
      Comments

      The wing phenotype of hrg10/hrgP1 flies is indistinguishable from that of hrgP1 homozygotes.

      (Murata et al., 1996)
      Images (0)
      Mutant
      Wild-type
      Stocks (4)
      Notes on Origin
      Discoverer

      Separable from: a lethal mutation.

      (Murata et al., 2001)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      hrg10
      (Pak et al., 2011, Cook and Cook, 2010.5.7, Christensen et al., 2008.9.3)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)