FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mysdin.UAS
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General Information
Symbol
Dmel\mysdin.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0061016
Feature type
allele
Associated gene
Dmel\mys
Associated Insertion(s)
Carried in Construct
P{UAS-mys.din}
Also Known As
UAS-βPS, UAS-mys
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Martin-Bermudo and Brown, 1996)
Progenitor genotype
mysdin
(Martin-Bermudo and Brown, 1996)
Carried in construct
P{UAS-mys.din}
Cytology
Description

UASt regulatory sequences drive expression of mys.

(Martin-Bermudo and Brown, 1996)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
mys
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Overexpression of ifScer\UAS.cMBa and mysdin.Scer\UAS in the somatic muscle under the control of Scer\GAL4Mef2.PR leads to pointed morphology of the muscle ends and subsequent torn muscles.

      (Gilsohn and Volk, 2010)

      Expression of mysdin.Scer\UAS and ifScer\UAS.cMBa under the control of Scer\GAL4how-24B results in a muscle-detachment phenotype.

      (Tanentzapf et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4Kr.PM/mysdin.UAS rescues mys11

      (Schock and Perrimon, 2003)
      Partially rescues

      mysdin.UAS/Scer\GAL448Y partially rescues mys11

      (Martin-Bermudo et al., 1999)

      Scer\GAL4twi.PG, Scer\GAL4how-24B, mysdin.UAS partially rescues mys11

      (Martin-Bermudo et al., 1999)
      Comments

      The addition of mysdin.Scer\UAS driven by Scer\GAL4Kr.PM rescues the germ band retraction defects seen embryos that are mys11 for both in maternal and zygotic mys.

      (Schock and Perrimon, 2003)

      Rescues the ability of the endodermal midgut cells of embryos that lack maternal and zygotic mys function (derived from homozygous mys11 female germline clones) to send projections and to migrate, although there is a small delay in migration, when expressed under the control of Scer\GAL448Y. The visceral mesoderm and germband retraction defects are not rescued in these embryos. mysdin.Scer\UAS expressed under the control of both Scer\GAL4twi.PG and Scer\GAL4how-24B rescues the visceral mesoderm defects of embryos that lack maternal and zygotic mys function (derived from homozygous mys11 female germline clones) but does not rescue the migration defects of the endodermal midgut cells in these embryos.

      (Martin-Bermudo et al., 1999)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mysdin.Scer\UAS
      mysdin.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (10)