FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\stckunspecified
Open Close
General Information
Symbol
Dmel\stckunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0062422
Feature type
allele
Associated gene
Dmel\stck
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        More than 85% of hemizygous embryos die. Those larvae that survive are significantly shorter than normal, are nearly immobile and die within 24 hours of hatching.

        (Clark et al., 2003)

        Homozygotes die as early larvae. Homozygous clones in the wing produce discrete, round blisters of variable size. These blisters can be located anywhere on the wing. Wing venation is normal. Homozygous embryos show excessive contractions of the segmental muscles just before hatching. Hatched larvae fail to grow.

        (Prout et al., 1997)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        Statement
        Reference

        stck[+]/stckunspecified is an enhancer of visible | recessive phenotype of mys8

        (Prout et al., 1997)

        stck[+]/stckunspecified is an enhancer of visible | recessive phenotype of mysb9

        (Prout et al., 1997)
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        stck[+]/stckunspecified is an enhancer of wing phenotype of mys8

        (Prout et al., 1997)

        stck[+]/stckunspecified is an enhancer of wing phenotype of mysb9

        (Prout et al., 1997)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Shows a weak genetic interaction with mys8 and mysb9; the frequency of held-out wings but not the frequency of blisters in mys8 or mysb9 single hemizygotes is increased if they are also heterozygous for stckunspecified.

        (Prout et al., 1997)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        stckunspecified is rescued by stck+tCa

        (Clark et al., 2003)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        stckunspecified
        unspecified
        (Prout et al., 1997)
        Name Synonyms
        Secondary FlyBase IDs
          References (3)