FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\vrik11805
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General Information
Symbol
Dmel\vrik11805
Species
D. melanogaster
Name
FlyBase ID
FBal0063674
Feature type
allele
Associated gene
Dmel\vri
Associated Insertion(s)
P{lacW}vrik11805
Carried in Construct
Also Known As
vri8
Key Links
Genomic Maps

Allele class

antimorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

antimorphic allele - genetic evidence

(George and Terracol, 1997)
Mutagen
P-element activity
(George and Terracol, 1997)
Progenitor genotype
Associated Insertion(s)
P{lacW}vrik11805
Cytology
Description

Lesion is at -57bp.

(Szuplewski et al., 2003)

P{lacW} insertion maps to position -57 upstream of the longest cDNA (e2) 5' end.

(George and Terracol, 1997)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous embryo head skeleton is defective. In some embryos the germ band remains extended, suggesting defects in germ band retraction. Some embryos are convoluted, the ventral denticles extend laterally and filzkorper are internal and present an abnormal morphology. Hemizygotes die as larvae.

      (George and Terracol, 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      vrik11805 is an enhancer of phenotype of dpphr4

      (George and Terracol, 1997)

      vrik11805 is an enhancer of phenotype of dpphr27

      (George and Terracol, 1997)

      vrik11805 is an enhancer of phenotype of ea161.13

      (George and Terracol, 1997)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      This allele was listed in the BDGP database as a lethal or sterile line during the period 1994-1999, but was discarded from the gene disruption project prior to the summary publication (FBrf0111489). Reasons for excluding lines from the collection described in FBrf0111489 include presence of more than one P insertion on the mutant chromosome, separation of lethality (or sterility) from the location of the insertion, and loss of lethality (or sterility) from the stock. Further information is available from http://www.fruitfly.org/bfd/ and from Dr. Spradling (spradling@mail1.ciwemb.edu).

      Complements: cype03771.

      (BDGP Project Members, 1994-1999)

      Mobilisation of the P{lacW} reveals the insertion is responsible for the mutant phenotype.

      (George and Terracol, 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      vri8
      (Szuplewski et al., 2003, George and Terracol, 1997)
      vrik11805
      Name Synonyms
      Secondary FlyBase IDs
        References (3)