FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Egmk14708
Open Close
General Information
Symbol
Dmel\Egmk14708
Species
D. melanogaster
Name
FlyBase ID
FBal0064096
Feature type
allele
Associated gene
Dmel\Egm
Associated Insertion(s)
P{lacW}Egmk14708
Carried in Construct
Also Known As
l(2)k14708
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Mourikis, 2006.3.2)
Mutagen
P-element activity
(Mourikis, 2006.3.2, Roch et al., 1998, BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}Egmk14708
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Egmk14708 heterozygous females live longer (18.4% more on average) than control flies. A similar longevity phenotype is observed for Egmk14708 flies kept at a higher temperature (29oC).

      (Mourikis et al., 2006)

      Lethality occurs during third instar larval or pupal stages. Mutants exhibit visible disc abnormalities: very small or no discs. Clones induced in wild type discs are of normal size and shape.

      (Roch et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Egmk14708 is rescued by Egm+tMa

      (Mourikis et al., 2006)
      Comments

      Expression of the Egm+tMa transgene rescues the lethality of Egmk14708 flies.

      (Mourikis et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      I. Kiss.

      (BDGP Project Members, 1994-1999)
      Comments
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      147/8
      (Roch et al., 1998)
      EgmP
      (Mourikis, 2006.3.2, Mourikis et al., 2006, Mourikis et al., 2006)
      Egmk14708
      l(2)k14708
      (Mourikis et al., 2006, Spradling et al., 1999)
      l(2)k14708k14708
      (BDGP Project Members, 1994-1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)