FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\blwk04409
Open Close
General Information
Symbol
Dmel\blwk04409
Species
D. melanogaster
Name
FlyBase ID
FBal0064635
Feature type
allele
Associated gene
Dmel\blw
Associated Insertion(s)
P{lacW}blwk04409
Carried in Construct
Also Known As
l(2)k4409
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}blwk04409
Cytology
Description

Insertion into an intron of the blw transcription unit.

(Galloni and Edgar, 1999)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Larval growth arrest, L1 stage. 20% survive until 4 days after hatching. 16% survive until 6 days after hatching. DNA replication continues at a reduced level compared to wild type. Mutant phenotype is cell autonomous. Mutant clones in the wing disc show a severe size reduction. Mosaic adults look normal. Mutant clones in the eye survive well.

      (Galloni and Edgar, 1999)

      Hemizygous lethal.

      (Jacobs et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      blwk04409 has phenotype, suppressible by Dphs.PD

      (Galloni and Edgar, 1999)

      blwk04409 has phenotype, suppressible by E2f1hs.PD

      (Galloni and Edgar, 1999)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      blwk00212

      (BDGP Project Members, 1994-1999)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      I. Kiss.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      blwk04409
      l(2)k00212k04409
      l(2)k4409
      (Galloni and Edgar, 1999, Jacobs et al., 1998)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)