ATP5A, ATPsyn-α, ATPsynα, C-V-α, ATP synthase subunit alpha
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.52
There is only one protein coding transcript and one polypeptide associated with this gene
F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\blw using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\blw in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
blw mutants display phenotypes that affect lipid storage and mitochondrial electron transport chain activity resulting in a reduction in ATP production and an accumulation of reactive oxygen species.
Production of reactive oxygen species is enhanced in Invadolysin mutant mitochondria.
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
Identification: One of a collection of genes identified with defective larval growth that extend larval life.
Postmeiotic differentiation defect.