FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\crol06470
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General Information
Symbol
Dmel\crol06470
Species
D. melanogaster
Name
FlyBase ID
FBal0064730
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description

P{PZ} insertion within the first intron.

Allele components
Component
Use(s)
Inserted element
Encoded product / tool
Mutations Mapped to the Genome
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

2-3% of crol06470/crolk08217 mutant animals are able to eclose from the pupal case, though these adults have severe morphological defects. 71% of these escapers have strongly misshapen legs, often with a severe kink in the femur. All escapers also display wing defects. Over half have held out wings with a partial (blister) or complete (balloon) separation of the dorsal and ventral wing surfaces, while the remainder have either malformed or completely unfolded wings. The blisters seen are generally large and do not appear to have sharp boundaries.

Homozygotes display a lethal phenotype indistinguishable from that of crol04418.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement
Reference

crol06470 is an enhancer of wing phenotype of if3

NOT Enhancer of
Statement
Reference

crol06470 is a non-enhancer of wing phenotype of mys8

Additional Comments
Genetic Interactions
Statement
Reference

The addition of crol06470 enhances the wing blistering phenotype of if3/Y flies by 3-4 fold. The addition of crol06470 does not enhance the wing blistering phenotype of mys8/Y flies.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
crol06470
l(2)0441806470
Name Synonyms
Secondary FlyBase IDs
    References (4)