FlyBase Allele Report: Dmel\18w[k02701]

General Information

Symbol

Dmel\18w^k02701

Species

D. melanogaster

Name

FlyBase ID

FBal0065575

Feature type

allele

Associated gene

Dmel\18w

Associated Insertion(s)

P{lacW}18w^k02701

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}18w^k02701

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:20,111,507..20,111,507 [+]

(Sharrock et al., 2022, Yagi et al., 2010, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal

(Yagi et al., 2010)

lethal (with 18w^Δ7-35)

(Kahsai et al., 2016)

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

partially lethal - majority die (with 18w^Δ7-35)

(Yagi et al., 2010)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

18w^k02701/18w^Δ7-35, Toll-6^ex13 has lethal phenotype

(Yagi et al., 2010)

18w^k02701/18w^Δ7-35, Df(3L)Brd15/Tollo⁵⁸ has lethal phenotype

(Yagi et al., 2010)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

18w^Δ7-35/18w^k02701; Toll-6^ex13/Toll-6^ex13 double mutants display 66% lethality.

18w^Δ7-35/18w^k02701; Tollo⁵⁸/Df(3L)Brd15 double mutants are lethal.

(Yagi et al., 2010)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

18w⁰⁰⁰⁵³

(BDGP Project Members, 1994-1999)

Fails to complement

18w^Δ7-35

(Kahsai et al., 2016)

18w⁰⁰⁰⁵³

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

10518

y¹ w^67c23; P{lacW}18w^k02701/CyO

Kyoto

111152

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{neoFRT}42D P{lacW}18w^k02701 /CyO y⁺

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

Complements: mus209⁰²⁴⁴⁸. Complements: l(2)k08002^k08002. Complements: Ate1^k10809. Complements: hts^k14523. Complements: l(2)s1866^s1866.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

18w^k02701

(Yagi et al., 2010)

l(2)k02701

(Spradling et al., 1999)

toll-2^K02701

(Sharrock et al., 2022)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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