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General Information
Symbol
Dmel\pblS008320
Species
D. melanogaster
Name
FlyBase ID
FBal0082374
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{lacW} insertion in the open reading frame of the 1A cDNA.

Insertion components
P{lacW}pblS008320
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Early lethal.

Embryos exhibit severe fasciculation defects, loss of neurons and concommitant increase in the size of the remaining cells. Mutants display gross defects in the axonal trajectories in the PNS. The intersegmental nerve grows from the dorsal cluster along aberrant pathways and often fails to connect to the lateral PNS cluster. Axons also cross segment boundaries in the dorsal, lateral and ventro-lateral region.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Excision of the P{lacW} is accompanied by a reversion to wild-type.

Δ2-3 induced reversion demonstrates the insertion is responsible for the lethal phenotype.

External Crossreferences and Linkouts ( 3 )
Crossreferences
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (6)