FlyBase Allele Report: Dmel\gro[E75]

General Information

Symbol

Dmel\gro^E75

Species

D. melanogaster

Name

FlyBase ID

FBal0082903

Feature type

allele

Associated gene

Dmel\gro

Associated Insertion(s)

Carried in Construct

Also Known As

E(spl)^E75

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Preiss et al., 1988)

Progenitor genotype

Cytology

Polytene chromosomes normal.

(Preiss et al., 1988)

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal

(Fischer-Vize et al., 1992)

lethal (with Df(3R)R20)

(Wurmbach and Preiss, 2014)

lethal (with Df(3R)R27)

(Wurmbach and Preiss, 2014)

lethal (with Df(3R)R70)

(Wurmbach and Preiss, 2014)

lethal (with Df(3R)R75)

(Wurmbach and Preiss, 2014)

lethal (with Df(3R)X13)

(Wurmbach and Preiss, 2014)

lethal (with T(2;3)R72)

(Wurmbach and Preiss, 2014)

lethal | neurogenic phenotype

(Preiss et al., 1988)

viable (with Df(3R)Espl-X10)

(Wurmbach and Preiss, 2014)

Phenotype Manifest In

Detailed Description

Statement

Reference

Shows lethality from the first larval instar to the pupal stage when heterozygous with the MBT chromosome.

(Riede, 2001)

Heterozygotes that are also heterozygous for gro^BFP2 have eye defects that are similar but not identical to gro^BFP2 homozygotes. Homozygous mutant clones in the eye show ommatidial defects, often having extra photoreceptors.

(Fischer-Vize et al., 1992)

Weak neurogenic phenotype.

(Preiss et al., 1988)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

gro^E75/gro[+] is a suppressor of visible | heat sensitive phenotype of H^C2.hs

(Johannes and Preiss, 2002)

Other

Statement

Reference

Df(3R)mbt^P, gro^E75 has lethal | pupal stage phenotype

(Riede, 2001)

gro^E75, srn⁸⁸ has lethal | larval stage phenotype

(Riede, 2001)

Phenotype Manifest In

Suppressor of

Statement

Reference

gro^E75/gro[+] is a suppressor of wing vein | ectopic | heat sensitive phenotype of H^C2.hs

(Johannes and Preiss, 2002)

gro^E75/gro[+] is a suppressor of wing | heat sensitive phenotype of H^C2.hs

(Johannes and Preiss, 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Can be rescued by a gro^unspecified transgene.

(Preiss, 2000.2.18)

Fails to complement the MBT chromosome for viability.

(Riede, 1996)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Preiss.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

E(spl)^E75

(Johannes and Preiss, 2002, Fischer-Vize et al., 1992, Preiss et al., 1988)

E(spl)^r20

gro^E75

(Wurmbach and Preiss, 2014)

Name Synonyms

Secondary FlyBase IDs

FBal0003341

References (10)

Report Sections

Open Close