FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\spzunspecified
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General Information
Symbol
Dmel\spzunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0086322
Feature type
allele
Associated gene
Dmel\spz
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mutant flies show reduced survival compared to wild-type controls after natural infection with B. bassiana or after challenge with a needle contaminated with E. faecalis.

        (Leclerc et al., 2006)

        Embryos derived from spzunspecified mutant females are dorsalised. Germline-dependent.

        (Tearle and Nusslein-Volhard, 1987)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Suppressed by
        Statement
        Reference

        spzunspecified has phenotype, suppressible by cactSu

        (Belvin et al., 1995)
        Suppressor of
        Statement
        Reference

        spz[+]/spzunspecified is a suppressor of embryonic/first instar larval cuticle phenotype of Egfrt1

        (Morisato, 2001)

        spz[+]/spzunspecified is a suppressor of ventral furrow | ectopic phenotype of Egfrt1

        (Morisato, 2001)

        spz[+]/spzunspecified is a suppressor of ventral furrow | increased number phenotype of Egfrt1

        (Morisato, 2001)
        Other
        Statement
        Reference

        Egfrt1, spz[+]/spzunspecified has ventral furrow phenotype

        (Morisato, 2001)

        Egfrt1, spzunspecified has ventral furrow phenotype

        (Morisato, 2001)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Embryos derived from Egfrt1 ; spzunspecified/+ females fail to invaginate ventral furrows and their cuticles show a reduction in ventral fates as compared to embryos laid by Egfrt1 single mutant females.

        (Morisato, 2001)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        spzunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (7)