FlyBase Allele Report: Mmus\Ctnnb1[arm.PW]

General Information

Symbol

Mmus\Ctnnb1^arm.PW

Species

M. musculus

Name

armadillo promoter construct of White

FlyBase ID

FBal0086800

Feature type

allele

Associated gene

Mmus\Ctnnb1

Associated Insertion(s)

Carried in Construct

P{arm-Mmus\Ctnnb1.W}

Transgenic product class

cDNA

(White et al., 1998)

wild_type

(White et al., 1998)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(White et al., 1998)

wild_type

(White et al., 1998)

Mutagen

in vitro construct

(White et al., 1998)

Progenitor genotype

Carried in construct

P{arm-Mmus\Ctnnb1.W}

Cytology

Description

An arm promoter fragment drives expression of a Mmus\Ctnnb1 cDNA.

(White et al., 1998)

Allele components

Component

Use(s)

Regulatory region(s)

arm

Encoded product / tool

Mmus\Ctnnb1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

Mmus\Ctnnb1^arm.PW is a suppressor of oocyte phenotype of arm¹

(White et al., 1998)

Mmus\Ctnnb1^arm.PW is a suppressor of nurse cell phenotype of arm¹

(White et al., 1998)

Mmus\Ctnnb1^arm.PW is a suppressor of egg chamber phenotype of arm¹

(White et al., 1998)

Mmus\Ctnnb1^arm.PW is a suppressor of embryo phenotype of arm¹

(White et al., 1998)

Mmus\Ctnnb1^arm.PW is a suppressor of embryonic/first instar larval cuticle phenotype of arm²

(White et al., 1998)

Mmus\Ctnnb1^arm.PW is a suppressor of cuticle phenotype of arm³

(White et al., 1998)

Other

Statement

Reference

Mmus\Ctnnb1^arm.PW, arm¹ has embryonic/first instar larval cuticle phenotype

(White et al., 1998)

Mmus\Ctnnb1^arm.PW, arm¹ has embryonic head phenotype

(White et al., 1998)

Mmus\Ctnnb1^arm.PW, arm³ has epidermis | ventral phenotype

(White et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

The defects seen in the ovarioles of females with homozygous arm¹ germline clones are completely rescued by Mmus\Catnb^arm.PW provided maternally. These rescued females can lay eggs, and a small fraction of them (2%) are fertilised. The embryos produced from these eggs lack the head regions and parts of the cuticle, resembling strong zygotic shg mutants. Slightly rescues the phenotype of hemizygous arm¹ embryos. Partially rescues the embryonic phenotype of homozygous arm³ embryos derived from females carrying homozygous arm³ germline clones when provided paternally. Partially rescues the cuticle phenotype of hemizygous embryos derived from females carrying homozygous arm² germline clones when provided maternally.

(White et al., 1998)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Extracts from embryos carrying Mmus\Catnb^arm.PW have been used in immunoprecipitation assays to investigate whether Mmus\Catnb protein interacts with α-Cat.

(White et al., 1998)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Mmus\Catnb^arm.PW

Mmus\Ctnnb1^arm.PW

Name Synonyms

armadillo promoter construct of White

(White et al., 1998)

Secondary FlyBase IDs

References (1)

Report Sections

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