FlyBase Allele Report: Dmel\mys[olfC-A459.1F1]

General Information

Symbol

Dmel\mys^{olfC-A459.1F1}

Species

D. melanogaster

Name

FlyBase ID

FBal0088728

Feature type

allele

Associated gene

Dmel\mys

Associated Insertion(s)

P{lArB}mys^{olfC-A459.1F1}

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Siddiqi, 1998)

Progenitor genotype

Associated Insertion(s)

P{lArB}mys^{olfC-A459.1F1}

Cytology

Description

The P{lArB} insertion is 1.7kb upstream of the mys coding region.

(Ayyub et al., 2000)

P{lArB} insertion a few kb 5' to the protein coding sequence of mys.

(Siddiqi, 1998)

Allele components

Component

Use(s)

Inserted element

P{lArB}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal smell perception (with mys⁸)

(Ayyub et al., 2000)

lethal | recessive

(Siddiqi, 1998)

Phenotype Manifest In

Detailed Description

Statement

Reference

mys⁸/mys^{olfC-A459.1F1} flies survive and show no defect in jumping ability. They show a reduced olfactory response to isoamyl acetate but respond normally to ethyl acetate. mys^{olfC-A459.1F1} fails to complement mys^olfC-x3, mys^olfC-x5, mys^olfC-x10 and mys^olfC-x17 when the olfactory response to isoamyl acetate is assayed. When the olfactory response to ethyl acetate is assayed, mys^{olfC-A459.1F1} fails to complement mys^olfC-x3 and mys^olfC-x10.