FlyBase Allele Report: Dmel\y[3c3]

General Information

Symbol

Dmel\y^3c3

Species

D. melanogaster

Name

FlyBase ID

FBal0091084

Feature type

allele

Associated gene

Dmel\y

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

loss of function allele

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

loss of function allele

(Morris et al., 1998)

Mutagen

ethyl methanesulfonate

(Morris et al., 1999)

Progenitor genotype

y¹

(Morris et al., 1999)

Cytology

Description

Structural alteration in the promoter.

(Morris et al., 1999)

Deletion of 3.6kb (from -1425bp to +2162bp relative to the y transcription start site) removing the promoter, 5' regulatory and transcribed sequences.

(Morris et al., 1998)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

AF074339

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal body color (with y^eve-700gin)

(Lee and Wu, 2006)

abnormal body color (with y^w-700gin)

(Lee and Wu, 2006)

Phenotype Manifest In

adult cuticle (with y^eve-700gin)

(Lee and Wu, 2006)

adult cuticle (with y^w-700gin)

(Lee and Wu, 2006)

wing (with y^eve-700gin)

(Lee and Wu, 2006)

wing (with y^w-700gin)

(Lee and Wu, 2006)

Detailed Description

Statement

Reference

Body colour: pigmentation score (where 1 = null/nearly null, 5 = wild type/nearly wild type): y^3c3/y^{P1\loxP.eve-700gin} : 4-4⁺ (wing), 4-4⁺ (body), y^3c3/y^{P1\loxP.hsp70-700gin} : 5 (wing), 5⁺ (body), y^3c3/y^{P1\loxP.w-700gin} : 4 (wing), 3⁺-4 (body).