FlyBase Allele Report: Dmel\Bx[EP1383]

General Information

Symbol

Dmel\Bx^EP1383

Species

D. melanogaster

Name

FlyBase ID

FBal0093491

Feature type

allele

Associated gene

Dmel\Bx

Associated Insertion(s)

P{EP}Bx^EP1383

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Pena-Rangel et al., 2002, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000, Zeng et al., 1998)

Progenitor genotype

Associated Insertion(s)

P{EP}Bx^EP1383

Cytology

Description

P{EP} insertion at -143bp relative to the start of the transcription unit.

(Abdelilah-Seyfried et al., 2000)

Insertion of a P{EP} element upstream of the 5' end of the Bxa transcript.

(Zeng et al., 1998)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:18,534,590..18,534,590 [+]

(Levine et al., 2007, Tsai et al., 2004, Pena-Rangel et al., 2002, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000, Zeng et al., 1998)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor rhythm

(Tsai et al., 2004)

visible, with Scer\GAL4^ptc-559.1

(Zeng et al., 1998)

visible, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

Phenotype Manifest In

dorsocentral bristle, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

scutellar bristle, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

scutum, with Scer\GAL4^ptc-559.1

(Zeng et al., 1998)

wing, with Scer\GAL4^ptc-559.1

(Zeng et al., 1998)

wing | ectopic, with Scer\GAL4^ptc-559.1

(Zeng et al., 1998)

Detailed Description

Statement

Reference

Mutant adults exhibit a less robust locomotor rhythm in constant darkness than control flies.

(Tsai et al., 2004)

Expression of Bx^EP1383 under the control of Scer\GAL4^sca-537.4 results in the loss of several scutellar and dorsocentral macrochaetae.

(Abdelilah-Seyfried et al., 2000)

Flies expressing Bx^EP1383 under the control of Scer\GAL4^ptc-559.1 show ectopic wing formation on the wing or notum.

(Zeng et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Bx^EP1383, Scer\GAL4^sca-537.4 has visible phenotype, non-enhanceable by H[+]/H^E21

(Abdelilah-Seyfried et al., 2000)

NOT suppressed by

Statement

Reference

Bx^EP1383, Scer\GAL4^sca-537.4 has visible phenotype, non-suppressible by H[+]/H^E21

(Abdelilah-Seyfried et al., 2000)

Enhancer of

Statement

Reference

Bx^EP1383/Scer\GAL4^pnr-MD237 is an enhancer of visible phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

Phenotype Manifest In

Enhancer of

Statement

Reference

Bx^EP1383/Scer\GAL4^pnr-MD237 is an enhancer of chaeta phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

NOT Enhancer of

Statement

Reference

Bx^EP1383/Scer\GAL4^sca-537.4 is a non-enhancer of phenotype of H^E21

(Abdelilah-Seyfried et al., 2000)

NOT Suppressor of

Statement

Reference

Bx^EP1383/Scer\GAL4^sca-537.4 is a non-suppressor of phenotype of H^E21

(Abdelilah-Seyfried et al., 2000)

Other

Statement

Reference

Bx^EP1383, Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+] has scutellum phenotype

(Pena-Rangel et al., 2002)

Bx^EP1383, Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+] has scutellar bristle phenotype

(Pena-Rangel et al., 2002)

Bx^EP1383, Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+] has dorsocentral bristle phenotype

(Pena-Rangel et al., 2002)

Bx^EP1383, Scer\GAL4^pnr-MD237, pnr^MD237 has scutellum phenotype

(Pena-Rangel et al., 2002)

Bx^EP1383, Scer\GAL4^pnr-MD237, pnr^MD237 has scutellar bristle phenotype

(Pena-Rangel et al., 2002)

Bx^EP1383, Scer\GAL4^pnr-MD237, pnr^MD237 has dorsocentral bristle phenotype

(Pena-Rangel et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

pnr^MD237/+ adults expressing Bx^EP1383 under the control of Scer\GAL4^pnr-MD237 have a deformed scutellum and show loss or gain of dorsocentral and scutellar macrochaetae.

(Pena-Rangel et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237.

(Pena-Rangel et al., 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Bx^EP1383

EP(X)1383

(Abdelilah-Seyfried et al., 2000)

EP1383

(Zeng et al., 1998)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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