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General Information
Symbol
Dmel\Su(z)123
Species
D. melanogaster
Name
FlyBase ID
FBal0094495
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
l(3)76BDo1
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

G19921738A

Reported nucleotide change:

G?A

Amino acid change:

W298term | Su(z)12-PA; W298term | Su(z)12-PB

Reported amino acid change:

W298term

Comment:

TGG to TGA

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: W298term.

Nucleotide substitution: G?A.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Su(z)125/Su(z)123 animals develop into pharate adults with strong posteriorly directed homeotic transformations. Sex combs are present on the first tarsal segment of the meso- and metathoracic legs in males, the antennae are partially transformed into legs and the wings are much smaller than normal and are partially transformed into halteres. Eggs are not recovered from females carrying homozygous germ-line clones.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhancer of
Statement
Reference

Su(z)123/Su(z)12[+] is a non-enhancer of visible phenotype of E2f1UAS.cNa, Scer\GAL4Act88F.PD

Su(z)123/Su(z)12[+] is a non-enhancer of visible phenotype of DpUAS.cDa, E2f1UAS.cNa, Scer\GAL4GMR.PU

Suppressor of
Statement
Reference

Su(z)123/Su(z)12[+] is a suppressor of visible phenotype of E2f1dsRNA.UAS.cJa, Scer\GAL4GMR.PU

Su(z)123/Su(z)12[+] is a suppressor | partially of visible phenotype of E2f1dsRNA.UAS.cJa, Scer\GAL4ptc-559.1

NOT Suppressor of
Statement
Reference

Su(z)123/Su(z)12[+] is a non-suppressor of visible phenotype of E2f1UAS.cNa, Scer\GAL4Act88F.PD

Su(z)123/Su(z)12[+] is a non-suppressor of visible phenotype of DpUAS.cDa, E2f1UAS.cNa, Scer\GAL4GMR.PU

Phenotype Manifest In
NOT Enhancer of
Statement
Reference

Su(z)123/Su(z)12[+] is a non-enhancer of wing phenotype of E2f1UAS.cNa, Scer\GAL4Act88F.PD

Su(z)123/Su(z)12[+] is a non-enhancer of eye phenotype of DpUAS.cDa, E2f1UAS.cNa, Scer\GAL4GMR.PU

Suppressor of
Statement
Reference

Su(z)123/Su(z)12[+] is a suppressor of eye phenotype of E2f1dsRNA.UAS.cJa, Scer\GAL4GMR.PU

NOT Suppressor of
Statement
Reference

Su(z)123/Su(z)12[+] is a non-suppressor of wing phenotype of E2f1UAS.cNa, Scer\GAL4Act88F.PD

Su(z)123/Su(z)12[+] is a non-suppressor of eye phenotype of DpUAS.cDa, E2f1UAS.cNa, Scer\GAL4GMR.PU

Additional Comments
Genetic Interactions
Statement
Reference

The disorganised eye phenotype caused by expression of sensScer\UAS.cNa under the control of Scer\GAL4lz-gal4 is suppressed by Su(z)123.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (10)