FB2026_02 , released June 18, 2026
Allele: Dmel\ifc59I
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General Information
Symbol
Dmel\ifc59I
Species
D. melanogaster
Name
FlyBase ID
FBal0094521
Feature type
allele
Associated gene
Dmel\ifc
Associated Insertion(s)
P{lacW}ifc59I
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Basu and Li, 1998)
Mutagen
P-element activity
(Basu and Li, 1998)
Progenitor genotype
Associated Insertion(s)
P{lacW}ifc59I
Cytology
Description

Insertion of P{lacW} 262bp upstream of the putative initiator ATG, in the same orientation as the ifc transcription unit.

(Basu and Li, 1998)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Small testes with large deposits of cellular debris indicating degeneration. Spermatids have misshapen nuclei. Nebenkern are misshapen and are associated with multiple nuclei - phenotype characteristic of cytokinesis failure. Mutants show meiotic spindle abnormalities. Haphazard arrays of microtubules are evident in place of symmetrical spindle apparatus. Astral arrays of microtubules are seldom seen. Heterozygotes with ifc1 show male sterility and abnormal spermatids.

      (Basu and Li, 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      ifc1

      (Basu and Li, 1998)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Excision of the P{lacW} can revert the full range of mutant phenotypes to wild type.

      (Basu and Li, 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      des-159I
      (Basu and Li, 1998)
      ifc59I
      Name Synonyms
      Secondary FlyBase IDs
        References (1)