FlyBase Allele Report: Dmel\RpS21[R12]

General Information

Symbol

Dmel\RpS21^R12

Species

D. melanogaster

Name

FlyBase ID

FBal0096734

Feature type

allele

Associated gene

Dmel\RpS21

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Torok et al., 1999)

Progenitor genotype

RpS21^k16814

(Torok et al., 1999)

Cytology

Description

Imprecise excision of the P{lacW} element, resulting in an approximately 2.5kb deletion which removes part of the 5'UTR and upstream control and promoter region.

(Torok et al., 1999)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate

(Torok et al., 1999)

decreased body size | adult stage | dominant

(Torok et al., 1999)

lethal - all die before end of larval stage | recessive

(Torok et al., 1999)

Minute

(Marygold et al., 2007)

some die during larval stage | recessive

(Torok et al., 1999)

visible | dominant

(Torok et al., 1999)

Phenotype Manifest In

macrochaeta

(Torok et al., 1999)

scutum

(Torok et al., 1999)

Detailed Description

Statement

Reference

Heterozygotes have short bristles, a reduced body size and a 4 day delay in eclosion. A partial cleft extending anteriorly from the scutoscutellar suture is seen on both sides of the scutum. Homozygotes die as second and early third instar larvae.

(Torok et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

RpS21^R12 is rescued by RpS21^+t2.8

(Torok et al., 1999)

Comments

One copy of RpS21^+t2.8 rescues the RpS21^R12 Minute phenotype. The lethality of RpS21^R12 homozygotes is rescued by two copies of RpS21^+t2.8.

(Torok et al., 1999)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a w^- revertant.

(Torok et al., 1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Df(2L)k168-14^R12

(Torok et al., 1999)

RpS21^R12

l(2)k168-14^R12

(Torok et al., 1999)

oho23B^R12

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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