FB2026_02 , released June 18, 2026
Allele: Dmel\kenok
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General Information
Symbol
Dmel\kenok
Species
D. melanogaster
Name
okina
FlyBase ID
FBal0096863
Feature type
allele
Associated gene
Dmel\ken
Associated Insertion(s)
P{}kenok
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Lukacsovich et al., 1999)
Progenitor genotype
Associated Insertion(s)
P{}kenok
Cytology
Description

Insertion between the translation start site and the transcription start site.

(Lukacsovich et al., 2003)

P-element insertion in the ken gene (at position 16,292-16,300, coordinates according to EMBL accession record AB010261).

(Lukacsovich et al., 1999)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      8% of homozygous males have aberrant terminalia; some of them appear to lack external genitalia, which remain inside the abdominal cuticle. Homozygotes have unpigmented aristae. The genital disc is malformed in ken1/kenok mutant males and some discs are split into two subdivisions.

      (Lukacsovich et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      kenok has male terminalia phenotype, enhanceable by cadmd509/cad[+]

      (Lukacsovich et al., 2003)

      kenok has terminalia phenotype, enhanceable by cadmd509/cadmd509

      (Lukacsovich et al., 2003)

      kenok has terminalia phenotype, enhanceable by dppd5/dpp[+]

      (Lukacsovich et al., 2003)

      kenok has terminalia phenotype, enhanceable by tll[+]/tlll49

      (Lukacsovich et al., 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      cadmd509 markedly increases the frequency of terminal defects in kenok homozygous adults; the frequency of male terminal defects is 8% in kenok homozygotes, 30% if they are also heterozygous for cadmd509 and 87% if they are also homozygous for cadmd509. The frequency of terminal defects in kenok homozygous adults is increased by tlll49/+. increased by dppd5/+.

      (Lukacsovich et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      kenok is rescued by ken+t9

      (Lukacsovich et al., 2003)
      Partially rescued by

      kenok is partially rescued by kenhs.PL

      (Lukacsovich et al., 2003)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (3)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Etymology: mutant is named "okina" (which in Japanese means a respectable old man with a white beard) since the aristae of mutant flies are unpigmented. Excision of the P-element can revert the mutant phenotype.

      (Lukacsovich et al., 2003)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      kenok
      kenokina
      okina
      (Lukacsovich et al., 1999)
      Name Synonyms
      okina
      (Lukacsovich et al., 2003)
      Secondary FlyBase IDs
        References (2)