FlyBase Allele Report: Dmel\cad[md509]

General Information

Symbol

Dmel\cad^md509

Species

D. melanogaster

Name

FlyBase ID

FBal0155515

Feature type

allele

Associated gene

Dmel\cad

Associated Insertion(s)

P{GawB}cad^md509

Carried in Construct

Also Known As

Cad-GAL4, caudal-Gal4

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Lukacsovich et al., 2003)

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GawB}cad^md509

Cytology

Description

P{GawB} insertion in the cad locus.

(Lukacsovich et al., 2003)

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Mutant adults do not show terminal defects.

(Lukacsovich et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

cad^md509/cad[+] is an enhancer of male terminalia phenotype of ken^ok

(Lukacsovich et al., 2003)

cad^md509/cad^md509 is an enhancer of terminalia phenotype of ken^ok

(Lukacsovich et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

cad^md509 markedly increases the frequency of terminal defects in ken^ok homozygous adults; the frequency of male terminal defects is 8% in ken^ok homozygotes, 30% if they are also heterozygous for cad^md509 and 87% if they are also homozygous for cad^md509.

(Lukacsovich et al., 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

3042