FlyBase Allele Report: Dmel\aos[GMR.PS]

General Information

Symbol

Dmel\aos^GMR.PS

Species

D. melanogaster

Name

glass multimer reporter construct of Sawamoto

FlyBase ID

FBal0097067

Feature type

allele

Associated gene

Dmel\aos

Associated Insertion(s)

Carried in Construct

P{GMR-argos.S}

Also Known As

GMR-argos

Key Links

Transgenic product class

cDNA

(Sawamoto et al., 1998)

wild_type

(Sawamoto et al., 1998)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Sawamoto et al., 1998)

wild_type

(Sawamoto et al., 1998)

Mutagen

in vitro construct

(Sawamoto et al., 1998)

Progenitor genotype

Carried in construct

P{GMR-argos.S}

Cytology

Description

Expression of aos cDNA entire coding region, contained within a 2kb EcoRI fragment, is controlled by a GMR promoter.

(Sawamoto et al., 1998)

Allele components

Component

Use(s)

Regulatory region(s)

GMR

engineered transcription regulatory region

Encoded product / tool

aos

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Taguchi et al., 2000, Kramer et al., 1999, Sawamoto et al., 1998)

Phenotype Manifest In

cone cell

(Sawamoto et al., 1998)

eye

(Mallik and Lakhotia, 2009, Taguchi et al., 2000, Kramer et al., 1999, Sawamoto et al., 1998)

eye photoreceptor cell

(Taguchi et al., 2000)

ommatidium

(Taguchi et al., 2000, Kramer et al., 1999)

photoreceptor

(Kramer et al., 1999)

photoreceptor neuron

(Sawamoto et al., 1998)

pigment cell

(Taguchi et al., 2000, Sawamoto et al., 1998)

Detailed Description

Statement

Reference

argos^GMR.PS eyes show roughening of the surface with disorganization of ommatidial arrays.

(Mallik and Lakhotia, 2009)

Flies carrying one copy of argos^GMR.PS have a mild rough eye phenotype, with the loss of some photoreceptor cells and pigmented lattices. Flies carrying two copies of argos^GMR.PS have smaller eyes with a more irregular array of ommatidia containing fewer cells than flies carrying one copy.

(Taguchi et al., 2000)

Eyes are small with fewer photoreceptor neurons per ommatidia. Photoreceptor neurons undergo apoptosis.

(Kramer et al., 1999)

Cell death during pupal development: numbers of photoreceptor, cone and pigment cells are reduced. Eye is slightly smaller than wild type. Phenotype is stronger for two copies of the transgene. Patterns of cell death and photoreceptor differentiation are normal in larval discs, however the number of dead cells in the pupal retina is increased.

(Sawamoto et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

SM2-1^SM2-1, aos^GMR.PS has visible phenotype

(Taguchi et al., 2000)

aos^GMR.PS, sty^SM3-5 has visible phenotype

(Taguchi et al., 2000)

aos^GMR.PS, sty^SM3-9 has visible phenotype

(Taguchi et al., 2000)

S^EF2-1, aos^GMR.PS has visible phenotype

(Taguchi et al., 2000)

aos^GMR.PS, cln^SF3-2 has visible phenotype

(Taguchi et al., 2000)

aos^GMR.PS, cln^SF3-3 has visible phenotype

(Taguchi et al., 2000)

aos^GMR.PS, bul^SF3-1 has visible phenotype

(Taguchi et al., 2000)

SM3-3^SM3-3, aos^GMR.PS has visible phenotype

(Taguchi et al., 2000)

SM3-2^SM3-2, aos^GMR.PS has visible phenotype

(Taguchi et al., 2000)

SM3-6^SM3-6, aos^GMR.PS has visible phenotype

(Taguchi et al., 2000)

SM3-8^SM3-8, aos^GMR.PS has visible phenotype

(Taguchi et al., 2000)

S^EM2-4, aos^GMR.PS has visible phenotype

(Taguchi et al., 2000)

EM3-1^EM3-1, aos^GMR.PS has visible phenotype

(Taguchi et al., 2000)

Phenotype Manifest In

Enhanced by

Statement

Reference

aos^GMR.PS has phenotype, enhanceable by EM3-1^EM3-1/EM3-1[+]

(Taguchi et al., 2000)

aos^GMR.PS has phenotype, enhanceable by S[+]/S^EM2-4

(Taguchi et al., 2000)

aos^GMR.PS has phenotype, enhanceable by S^EF2-1/S[+]

(Taguchi et al., 2000)

Suppressed by

Statement

Reference

aos^GMR.PS has phenotype, suppressible by SM2-1[+]/SM2-1^SM2-1

(Taguchi et al., 2000)

aos^GMR.PS has phenotype, suppressible by sty[+]/sty^SM3-9

(Taguchi et al., 2000)

aos^GMR.PS has phenotype, suppressible by SM3-2[+]/SM3-2^SM3-2

(Taguchi et al., 2000)

aos^GMR.PS has phenotype, suppressible by SM3-3[+]/SM3-3^SM3-3

(Taguchi et al., 2000)

aos^GMR.PS has phenotype, suppressible by SM3-6[+]/SM3-6^SM3-6

(Taguchi et al., 2000)

aos^GMR.PS has phenotype, suppressible by SM3-8^SM3-8/SM3-8[+]

(Taguchi et al., 2000)

aos^GMR.PS has phenotype, suppressible by bul[+]/bul^SF3-1

(Taguchi et al., 2000)

aos^GMR.PS has phenotype, suppressible by cln[+]/cln^SF3-2

(Taguchi et al., 2000)

aos^GMR.PS has phenotype, suppressible by cln[+]/cln^SF3-3

(Taguchi et al., 2000)

aos^GMR.PS has phenotype, suppressible by sty[+]/sty^SM3-5

(Taguchi et al., 2000)

aos^GMR.PS has phenotype, suppressible by sty^Δ5

(Kramer et al., 1999)

aos^GMR.PS has eye phenotype, suppressible by BacA\p35^GMR.PH

(Sawamoto et al., 1998)

aos^GMR.PS has photoreceptor neuron phenotype, suppressible by BacA\p35^GMR.PH

(Sawamoto et al., 1998)

aos^GMR.PS has pigment cell phenotype, suppressible by BacA\p35^GMR.PH

(Sawamoto et al., 1998)

aos^GMR.PS has cone cell phenotype, suppressible by BacA\p35^GMR.PH

(Sawamoto et al., 1998)

aos^GMR.PS has eye phenotype, suppressible by Df(3L)H99

(Sawamoto et al., 1998)

aos^GMR.PS has photoreceptor neuron phenotype, suppressible by Df(3L)H99

(Sawamoto et al., 1998)

aos^GMR.PS has pigment cell phenotype, suppressible by Df(3L)H99

(Sawamoto et al., 1998)

aos^GMR.PS has cone cell phenotype, suppressible by Df(3L)H99

(Sawamoto et al., 1998)

aos^GMR.PS has cone cell phenotype, suppressible by Ras85D^V12.hs

(Sawamoto et al., 1998)

aos^GMR.PS has eye phenotype, suppressible by Diap1^GMR.PH

(Sawamoto et al., 1998)

aos^GMR.PS has photoreceptor neuron phenotype, suppressible by Diap1^GMR.PH

(Sawamoto et al., 1998)

aos^GMR.PS has pigment cell phenotype, suppressible by Diap1^GMR.PH

(Sawamoto et al., 1998)

aos^GMR.PS has cone cell phenotype, suppressible by Diap1^GMR.PH

(Sawamoto et al., 1998)

aos^GMR.PS has eye phenotype, suppressible by Diap2^GMR.PH

(Sawamoto et al., 1998)

aos^GMR.PS has photoreceptor neuron phenotype, suppressible by Diap2^GMR.PH

(Sawamoto et al., 1998)

aos^GMR.PS has pigment cell phenotype, suppressible by Diap2^GMR.PH

(Sawamoto et al., 1998)

aos^GMR.PS has cone cell phenotype, suppressible by Diap2^GMR.PH

(Sawamoto et al., 1998)

NOT Suppressor of

Statement

Reference

aos^GMR.PS is a non-suppressor of phenotype of sty^Δ5

(Kramer et al., 1999)

Other

Statement

Reference

S^EF2-1, aos^GMR.PS has eye phenotype

(Taguchi et al., 2000)

S^EF2-1, aos^GMR.PS has ommatidium phenotype

(Taguchi et al., 2000)

SM2-1^SM2-1, aos^GMR.PS has ommatidium phenotype

(Taguchi et al., 2000)

aos^GMR.PS, sty^SM3-5 has eye phenotype

(Taguchi et al., 2000)

aos^GMR.PS, sty^SM3-5 has ommatidium phenotype

(Taguchi et al., 2000)

aos^GMR.PS, sty^SM3-9 has eye phenotype

(Taguchi et al., 2000)

aos^GMR.PS, sty^SM3-9 has ommatidium phenotype

(Taguchi et al., 2000)

aos^GMR.PS, cln^SF3-2 has eye phenotype

(Taguchi et al., 2000)

aos^GMR.PS, cln^SF3-2 has ommatidium phenotype

(Taguchi et al., 2000)

aos^GMR.PS, cln^SF3-3 has eye phenotype

(Taguchi et al., 2000)

aos^GMR.PS, cln^SF3-3 has ommatidium phenotype

(Taguchi et al., 2000)

aos^GMR.PS, bul^SF3-1 has eye phenotype

(Taguchi et al., 2000)

aos^GMR.PS, bul^SF3-1 has ommatidium phenotype

(Taguchi et al., 2000)

SM3-3^SM3-3, aos^GMR.PS has eye phenotype

(Taguchi et al., 2000)

SM3-3^SM3-3, aos^GMR.PS has ommatidium phenotype

(Taguchi et al., 2000)

S^EM2-4, aos^GMR.PS has eye phenotype

(Taguchi et al., 2000)

SM3-2^SM3-2, aos^GMR.PS has eye phenotype

(Taguchi et al., 2000)

SM3-2^SM3-2, aos^GMR.PS has ommatidium phenotype

(Taguchi et al., 2000)

SM3-6^SM3-6, aos^GMR.PS has eye phenotype

(Taguchi et al., 2000)

SM3-6^SM3-6, aos^GMR.PS has ommatidium phenotype

(Taguchi et al., 2000)

SM3-8^SM3-8, aos^GMR.PS has eye phenotype

(Taguchi et al., 2000)

SM3-8^SM3-8, aos^GMR.PS has ommatidium phenotype

(Taguchi et al., 2000)

S^EM2-4, aos^GMR.PS has ommatidium phenotype

(Taguchi et al., 2000)

EM3-1^EM3-1, aos^GMR.PS has eye phenotype

(Taguchi et al., 2000)

EM3-1^EM3-1, aos^GMR.PS has ommatidium phenotype

(Taguchi et al., 2000)

SM2-1^SM2-1, aos^GMR.PS has eye phenotype

(Taguchi et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

eye, non-suppressible { Hsrω[Sym.Scer\UAS], Hsrω[a.Sym.Scer\UAS], Scer\GAL4[GMR.PF] }

(Mallik and Lakhotia, 2009)

Eyes mutant for both sty^Δ5 and carrying argos^GMR.PS have a normal-size eye and an extra-R7 phenotype similar to that of sty^Δ5 alone.

(Kramer et al., 1999)

The mutant eye phenotype is suppressed by Iap2^GMR.PH, BacA\p35^GMR.PH, th^GMR.PH and Df(3L)H99. Flies carrying both Ras85D^V12.hs and argos^GMR.PS show a normal number of cone cells in most ommatidia.

(Sawamoto et al., 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

aos^GMR.PS

argos^GMR.PS

Name Synonyms

glass multimer reporter construct of Sawamoto

(Kramer et al., 1999, Sawamoto et al., 1998)

Secondary FlyBase IDs

References (4)

Report Sections

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