FlyBase Allele Report: Dmel\arm[G0192]

General Information

Symbol

Dmel\arm^G0192

Species

D. melanogaster

Name

FlyBase ID

FBal0103762

Feature type

allele

Associated gene

Dmel\arm

Associated Insertion(s)

P{lacW}arm^G0192

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Schäfer et al., 1999.12.2)

Progenitor genotype

Associated Insertion(s)

P{lacW}arm^G0192

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:1,892,909..1,893,637 [-]

(Peter et al., 2002, Benos et al., 2001, Schäfer et al., 1999.12.2)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

AJ300027

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Huntington's disease

modeled by Hsap\HTT^Q93.ex1.UAS

(Dupont et al., 2012)

modeled by Hsap\HTT^{128Q.1-336.UAS}

(Kaltenbach et al., 2007)

ameliorates Schimke immuno-osseous dysplasia

modeled by Marcal1^UAS.cBa

(Morimoto et al., 2016)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Schäfer et al., 1999.12.2)

lethal - all die during embryonic stage

(Peter et al., 2002)

some die during embryonic stage

(Peter et al., 2002)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

arm^G0192/arm[+] is a suppressor | partially of short lived phenotype of Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^elav.PU

(Dupont et al., 2012)

arm^G0192/arm[+] is a suppressor | partially of short lived phenotype of Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^Eaat1.PR

(Dupont et al., 2012)

arm^G0192 is a suppressor of visible phenotype of Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Other

Statement

Reference

L^si, arm^G0192, hyx^EY06898 has visible | adult stage phenotype

(Zhang et al., 2010)

Phenotype Manifest In

Suppressor of

Statement

Reference

arm^G0192 is a suppressor of eye phenotype of Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Other

Statement

Reference

L^si, arm^G0192, hyx^EY06898 has eye phenotype

(Zhang et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

arm^G0192/+ significantly partially suppresses the decreased lifespan seen in flies with expression of Hsap\HTT^{Q93.ex1p.Scer\UAS} driven by Scer\GAL4^elav.PU or Scer\GAL4^Eaat1.PR.

(Dupont et al., 2012)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

12156

P{lacW}arm^G0192 w^67c23/FM7c

Notes on Origin

Discoverer

Comments

P{lacW} not verified as causing the lethality.

(Schäfer et al., 1999.12.2)

External Crossreferences and Linkouts ( 1 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AJ300027

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Arm^G0192

(Zhang et al., 2010)

G0192

(Kaltenbach et al., 2007)

arm^G0192

(Dupont et al., 2012)

l(1)G0192

(Peter et al., 2002, Benos et al., 2001)

l(1)G0192^G0192

(Schäfer et al., 1999.12.2)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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