FlyBase Allele Report: Dmel\Dll[UAS.cBa]

General Information

Symbol

Dmel\Dll^UAS.cBa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Basler

FlyBase ID

FBal0104325

Feature type

allele

Associated gene

Dmel\Dll

Associated Insertion(s)

Carried in Construct

P{UAS-Dll.B}

Also Known As

UAS-Dll

Key Links

Transgenic product class

wild_type

(Dong et al., 2000)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Dong et al., 2000)

Mutagen

in vitro construct

(Dong et al., 2000)

Progenitor genotype

Carried in construct

P{UAS-Dll.B}

Cytology

Description

UAS regulatory sequences drive Dll expression.

(Dong et al., 2000)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Dll

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^dpp.blk1

(Dong et al., 2000)

Phenotype Manifest In

adult head, with Scer\GAL4^dpp.blk1

(Dong et al., 2000)

antenna | ectopic, with Scer\GAL4^dpp.blk1

(Dong et al., 2000)

arista | ectopic, with Scer\GAL4^dpp.blk1

(Dong et al., 2000)

leg | ectopic, with Scer\GAL4^dpp.blk1

(Dong et al., 2000)

wing, with Scer\GAL4^dpp.blk1

(Dong et al., 2000)

Detailed Description

Statement

Reference

Only small clones expressing Dll^Scer\UAS.cBa under the control of Scer\GAL4^Act5C.PP can be recovered in the proximal part of the antennal disc. Expression of Dll^Scer\UAS.cBa under the control of Scer\GAL4^dpp.blk1 results in the formation of ectopic antennal structures on the back of the head and ectopic leg tissue on the wing. Differentiation of antennal structures (primarily arista) in the proximal wing, and less frequently, in the proximal leg is seen.

(Dong et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Dll^UAS.cBa, Scer\GAL4^dpp.blk1 has visible phenotype, enhanceable by hth^UAS.GFP, Scer\GAL4^dpp.blk1

(Dong et al., 2000)

Phenotype Manifest In

Enhanced by

Statement

Reference

Dll^UAS.cBa, Scer\GAL4^dpp.blk1 has leg phenotype, enhanceable by hth^UAS.GFP, Scer\GAL4^dpp.blk1

(Dong et al., 2000)

Dll^UAS.cBa, Scer\GAL4^dpp.blk1 has adult head phenotype, enhanceable by hth^UAS.GFP, Scer\GAL4^dpp.blk1

(Dong et al., 2000)

Other

Statement

Reference

Dll^UAS.cBa, Scer\GAL4^dpp.blk1, hth^UAS.GFP has male genitalia phenotype

(Dong et al., 2000)

Dll^UAS.cBa, Scer\GAL4^dpp.blk1, hth^UAS.GFP has female genitalia phenotype

(Dong et al., 2000)

Dll^UAS.cBa, Scer\GAL4^dpp.blk1, hth^UAS.GFP has unguis phenotype

(Dong et al., 2000)

Dll^UAS.cBa, Scer\GAL4^dpp.blk1, hth^UAS.GFP has antenna | ectopic phenotype

(Dong et al., 2000)

Dll^UAS.cBa, Scer\GAL4^dpp.blk1, hth^UAS.GFP has arista | ectopic phenotype

(Dong et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of both Dll^Scer\UAS.cBa and hth^{Scer\UAS.T:Avic\GFP} under the control of Scer\GAL4^dpp.blk1 results in the formation of ectopic antennal structures in the leg (in 19% of animals), such as transformation of one of the tarsal claws to arista. Extra antennal tissue is induced on the head, with as many as three ectopic antennae on each side of the head. Aristae are induced on female and male genital disc derivatives (in 43% of animals). Ectopic antennal tissue is not seen in the genital disc derivatives if hth^{Scer\UAS.T:Avic\GFP} or Dll^Scer\UAS.cBa are expressed alone under the control of Scer\GAL4^dpp.blk1. Ectopic antennal tissue is not seen in the leg if hth^{Scer\UAS.T:Avic\GFP} is expressed alone under the control of Scer\GAL4^dpp.blk1, and is seen in less than 1% of animals when Dll^Scer\UAS.cBa alone is expressed under the control of Scer\GAL4^dpp.blk1.

(Dong et al., 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

78349

y¹ w^*; P{UAS-Dll.B}2

Notes on Origin

Discoverer

K. Basler

(Dong et al., 2000)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Dll^Scer\UAS.cBa

Dll^UAS.cBa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Basler

(Dong et al., 2000)

Secondary FlyBase IDs

References (5)

Report Sections

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