FB2026_02 , released June 18, 2026
Allele: Dmel\stauΔloop2.αTub67C.Tag:MYC
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General Information
Symbol
Dmel\stauΔloop2.αTub67C.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0104416
Feature type
allele
Associated gene
Dmel\stau
Associated Insertion(s)
Carried in Construct
P{αTub67C-stau.full}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Micklem et al., 2000)
Progenitor genotype
Carried in construct
P{αTub67C-stau.full}
Cytology
Description

The stau cDNA, which has had the amino acids that divide double stranded RNA Binding Domain 2 (dsRBD2) into two halves replaced by the corresponding 8 amino acid loop of dsRBD3, is driven by the αTub67C promoter and tagged at the amino terminus with Tag:MYC.

(Micklem et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
αTub67C
Encoded product / tool
stau
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Embryos that express both miraΔ103.αTub67C.T:Avic\GFP-m6 and stauΔloop2.αTub67C.T:Hsap\MYC in a stau2 background lack a posterior abdomen and form an anterior abdomen with complete reverse polarity.

      (Irion et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      stauΔloop2.αTub67C.Tag:MYC partially rescues stau2

      (Micklem et al., 2000)
      Comments

      Addition of stauΔloop2.αTub67C.T:Hsap\MYC to stau2 mothers gives little or no rescue of the stau posterior phenotype, none of the progeny of these flies hatch into larvae, and almost all develop less than one abdominal segment. However, the head skeleton defects seen in stau2 flies are rescued: 2/3 of embryos have wild-type heads (compared to none in stau2 alone) and the rest have much milder head defects.

      (Micklem et al., 2000)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      stauΔloop2.αTub67C.T:Hsap\MYC
      stauΔloop2.αTub67C.Tag:MYC
      stauΔloop2.
      (Irion et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)