FlyBase Allele Report: Dmel\upd1[unspecified]

General Information

Symbol

Dmel\upd1^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0117420

Feature type

allele

Associated gene

Dmel\upd1

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | adult stage

(Tettweiler et al., 2019)

visible (with Df(1)os1A2)

(Bach et al., 2003)

Phenotype Manifest In

eye

(Tettweiler et al., 2019)

eye (with Df(1)os1A2)

(Bach et al., 2003)

wing

(Badenhorst et al., 2002)

Detailed Description

Statement

Reference

upd1^unspecified/Df(1)os1A2 animals have a normally patterned eye that is considerably smaller than wild type.

(Bach et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

upd1^unspecified has abnormal size | adult stage phenotype, enhanceable by Hipk[+]/Hipk⁴

(Tettweiler et al., 2019)

upd1^unspecified/Df(1)os1A2 has visible phenotype, enhanceable by Socs36E^UASp.cCa/Scer\GAL4^ey.PH

(Bach et al., 2003)

upd1^unspecified/Df(1)os1A2 has visible phenotype, enhanceable by dome^UAS.cCGHa/Scer\GAL4^ey.PH

(Bach et al., 2003)

Suppressed by

Statement

Reference

upd1^unspecified/Df(1)os1A2 has visible phenotype, suppressible | partially by dpp^UAS.cRa/Scer\GAL4^ey.PH

(Bach et al., 2003)

upd1^unspecified/Df(1)os1A2 has visible phenotype, suppressible | partially by tkv^{Q253D.UAS.cLa}/Scer\GAL4^ey.PH

(Bach et al., 2003)

NOT suppressed by

Statement

Reference

upd1^unspecified/Df(1)os1A2 has visible phenotype, non-suppressible by Scer\GAL4^ey.PH/Stat92E^UAS.cPa

(Bach et al., 2003)

NOT Enhancer of

Statement

Reference

upd1^unspecified is a non-enhancer of visible phenotype of Scer\GAL4^GMR.PF, tkv^{Q253D.UAS.cLa}

(Bach et al., 2003)

NOT Suppressor of

Statement

Reference

upd1^unspecified is a non-suppressor of visible phenotype of Scer\GAL4^GMR.PF, tkv^{Q253D.UAS.cLa}

(Bach et al., 2003)

Phenotype Manifest In

Enhanced by

Statement

Reference

upd1^unspecified has eye phenotype, enhanceable by Hipk[+]/Hipk⁴

(Tettweiler et al., 2019)

upd1^unspecified/Df(1)os1A2 has eye phenotype, enhanceable by Socs36E^UASp.cCa/Scer\GAL4^ey.PH

(Bach et al., 2003)

upd1^unspecified/Df(1)os1A2 has eye phenotype, enhanceable by dome^UAS.cCGHa/Scer\GAL4^ey.PH

(Bach et al., 2003)

Suppressed by

Statement

Reference

upd1^unspecified/Df(1)os1A2 has eye phenotype, suppressible | partially by dpp^UAS.cRa/Scer\GAL4^ey.PH

(Bach et al., 2003)

upd1^unspecified/Df(1)os1A2 has eye phenotype, suppressible | partially by tkv^{Q253D.UAS.cLa}/Scer\GAL4^ey.PH

(Bach et al., 2003)

upd1^unspecified has wing phenotype, suppressible by E(bx)^Nurf301-2

(Badenhorst et al., 2002)

upd1^unspecified has wing phenotype, suppressible by Df(3L)3643

(Badenhorst et al., 2002)

NOT suppressed by

Statement

Reference

upd1^unspecified/Df(1)os1A2 has eye phenotype, non-suppressible by Scer\GAL4^ey.PH/Stat92E^UAS.cPa

(Bach et al., 2003)

NOT Enhancer of

Statement

Reference

upd1^unspecified is a non-enhancer of eye phenotype of Scer\GAL4^GMR.PF, tkv^{Q253D.UAS.cLa}

(Bach et al., 2003)

NOT Suppressor of

Statement

Reference

upd1^unspecified is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PF, tkv^{Q253D.UAS.cLa}

(Bach et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

The non-autonomous overgrowth phenotype caused by Df(1)ph^del clones in the eye is not suppressed if the clones are also mutant for upd1^unspecified.

(Feng et al., 2011)

The small eye phenotype of upd1^unspecified/Df(1)os1A2 flies is enhanced by expression of dome^{Scer\UAS.cCGHa} under the control of Scer\GAL4^ey.PH. Expression of Stat92E^Scer\UAS.cPa under the control of Scer\GAL4^ey.PH does not rescue the small eye phenotype of upd1^unspecified/Df(1)os1A2 flies. The small eye phenotype of upd1^unspecified/Df(1)os1A2 flies is enhanced by expression of Socs36E^{Scer\UAS.P\T.cCa} under the control of Scer\GAL4^ey.PH. The small eye phenotype of upd1^unspecified/Df(1)os1A2 flies is partly suppressed by expression of dpp^Scer\UAS.cRa or tkv^{Q253D.Scer\UAS.cLa} under the control of Scer\GAL4^ey.PH. The reduction in eye size seen in upd1^unspecified/Df(1)os1A2 flies is increased by expression of hh^N.Scer\UAS under the control of Scer\GAL4^ey.PH and extra bristles are seen in the eye.

(Bach et al., 2003)

The addition of E(bx)^Nurf301-2/+ or Df(3L)3643/+ suppresses the wings outstretched phenotype seen in upd1 mutants.

(Badenhorst et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

upd1^unspecified/Df(1)os1A2 is rescued by Scer\GAL4^ey.PH/upd1^UAS.cZa

(Bach et al., 2003)

Partially rescued by

upd1^unspecified is partially rescued by upd1^t5.8

(Sefton et al., 2000)

upd1^unspecified is partially rescued by upd1^t10

(Sefton et al., 2000)

Not rescued by

upd1^unspecified is not rescued by upd1^t4.8

(Sefton et al., 2000)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

os^unspecified

upd1^unspecified

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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