FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Madunspecified
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General Information
Symbol
Dmel\Madunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0118422
Feature type
allele
Associated gene
Dmel\Mad
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        The number of T bars per active zone and bouton surface area per active zone is increased compared to wild type in the boutons of muscle 6/7 in mutant third instar larvae. 37 +/- 4% detachment of the presynaptic membrane is seen.

        (McCabe et al., 2004)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        NOT Enhancer of
        Statement
        Reference

        Madunspecified is a non-enhancer of visible phenotype of hidGMR.PG

        (Bach et al., 2003)
        NOT Suppressor of
        Statement
        Reference

        Madunspecified is a non-suppressor of visible phenotype of hidGMR.PG

        (Bach et al., 2003)
        Phenotype Manifest In
        NOT Enhancer of
        Statement
        Reference

        Madunspecified is a non-enhancer of eye phenotype of hidGMR.PG

        (Bach et al., 2003)
        Suppressor of
        Statement
        Reference

        Mad[+]/Madunspecified is a suppressor of eye photoreceptor cell phenotype of Scer\GAL4ey.PH, dallyUAS.cJa

        (Kirkpatrick et al., 2006)

        dppd-ho/Madunspecified is a suppressor of phenotype of CycEJP

        (Horsfield et al., 1998)
        NOT Suppressor of
        Statement
        Reference

        Madunspecified is a non-suppressor of eye phenotype of hidGMR.PG

        (Bach et al., 2003)

        Mad[+]/Madunspecified is a non-suppressor of wing vein | ectopic phenotype of EgfrE1

        (Li and Li, 2003)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The reduction in the number of photoreceptors per ommatidia seen in eyes that express dallyScer\UAS.cJa under the control of Scer\GAL4ey.PH is suppressed in a Madunspecified/+ mutant background.

        (Kirkpatrick et al., 2006)

        The eye phenotype caused by expression of tkvQ253D.Scer\UAS.cLa under the control of Scer\GAL4GMR.PF is partially modified by Madunspecified.

        (Bach et al., 2003)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Madunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (9)