FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\dallyUAS.cJa
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General Information
Symbol
Dmel\dallyUAS.cJa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Jackson
FlyBase ID
FBal0083022
Feature type
allele
Associated gene
Dmel\dally
Associated Insertion(s)
Carried in Construct
P{UAS-dally.J}
Also Known As
UAS-dally, UAS-dally+
Key Links
Transgenic product class
cDNA
(Jackson et al., 1997)
wild_type
(Jackson et al., 1997)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Jackson et al., 1997)
wild_type
(Jackson et al., 1997)
Mutagen
in vitro construct
(Jackson et al., 1997)
Progenitor genotype
Carried in construct
P{UAS-dally.J}
Cytology
Description

dally cDNA is expressed under the control of UASt regulatory sequences.

(Jackson et al., 1997)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dally
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      anterior crossvein, with Scer\GAL4en-e16E

      (Kirkpatrick et al., 2006)

      dorsocentral bristle | increased number, with Scer\GAL4A9, dallygem

      (Kirkpatrick et al., 2006)

      dorsocentral bristle | increased number, with Scer\GAL4A9, dallyΔP-527/dallygem

      (Kirkpatrick et al., 2006)

      embryonic epidermis, with Scer\GAL4en-e16E

      (Tsuda et al., 1999)

      embryonic epidermis, with Scer\GAL4prd.RG1

      (Tsuda et al., 1999)

      eye, with Scer\GAL4ey.PH

      (Kirkpatrick et al., 2006)

      eye photoreceptor cell, with Scer\GAL4ey.PH

      (Kirkpatrick et al., 2006)

      female germline cell | increased number, with Scer\GAL4C587

      (Xia et al., 2012)

      female germline stem cell | increased number, with Scer\GAL4bab1-Pgal4-2

      (Guo and Wang, 2009)

      female germline stem cell | increased number, with Scer\GAL4C587

      (Guo and Wang, 2009)

      female germline stem cell | increased number, with Scer\GAL4ptc-559.1

      (Guo and Wang, 2009)

      female germline stem cell | increased number, with Scer\GAL4VP16.nanos.UTR

      (Guo and Wang, 2009)

      germarium, with Scer\GAL4C587

      (Xia et al., 2012)

      haltere, with Scer\GAL4en-e16E

      (Crickmore and Mann, 2007)

      haltere disc, with Scer\GAL4en-e16E

      (Crickmore and Mann, 2007)

      haltere disc posterior compartment, with Scer\GAL4en-e16E

      (de Navas et al., 2006)

      larval abdominal segmental nerve, with Scer\GAL4G14, Scer\GAL4how-24B

      (Fox and Zinn, 2005)

      larval intersegmental nerve branch ISNb of A1-7 | embryonic stage, with Scer\GAL4elav.PU

      (Cho et al., 2012)

      larval segmental nerve branch SNa of A1-7 | embryonic stage, with Scer\GAL4elav.PU

      (Cho et al., 2012)

      ommatidium, with Scer\GAL4ey.PH

      (Kirkpatrick et al., 2006)

      ovary, with Scer\GAL4C587

      (Xia et al., 2012)

      posterior crossvein, with Scer\GAL4en-e16E

      (Kirkpatrick et al., 2006)

      wing, with Scer\GAL4nub-AC-62

      (Avanesov et al., 2012)

      wing blade anterior compartment, with Scer\GAL4en-e16E

      (Kirkpatrick et al., 2006)

      wing blade posterior compartment, with Scer\GAL4en-e16E

      (Kirkpatrick et al., 2006)

      wing disc | larval stage, with Scer\GAL4C-765

      (Merino et al., 2022)

      wing margin bristle, with Scer\GAL4nub-AC-62

      (Avanesov et al., 2012)
      Detailed Description
      Statement
      Reference

      Expression of dallyScer\UAS.cJa under the control of Scer\GAL4nub-AC-62 does not induce wing margin scalloping but has weak effects on margin bristle number.

      (Avanesov et al., 2012)

      Embryos expressing dallyScer\UAS.cJa under the control of Scer\GAL4elav.PU show ISNb motor axon guidance defects (53.8% of hemisegments) and SNa motor axon guidance defects (25.5% of hemisegments).

      (Cho et al., 2012)

      Expression of dallyScer\UAS.cJa in the inner germarium sheath (IGS) cells under the control of Scer\GAL4C587 results in tumorous germaria that are filled with bam-negative GSC-like cells.

      (Xia et al., 2012)

      Expression of dallyScer\UAS.cJa under the control of Scer\GAL4C587, Scer\GAL4ptc-559.1 or Scer\GAL4nos.UTR.T:Hsim\VP16 results in the progressive accumulation of extra germline stem cell-like cells (the cells have spherical fusomes) in the ovarioles. The extra germline stem cell-like cells hardly differentiate in females expressing dallyScer\UAS.cJa under the control of Scer\GAL4C587, leaving large stage gaps between the germarium and the adjacent egg chamber. BrdU incorporation is seen in multiple two-cell clusters posterior and distant from the niche in germaria expressing dallyScer\UAS.cJa under the control of Scer\GAL4C587 (this is never seen in wild type).

      Expression of dallyScer\UAS.cJa under the control of Scer\GAL4bab1-Pgal4-2 results in the progressive accumulation of some extra germline stem cell-like cells in the ovarioles.

      Expression of dallyScer\UAS.cJa under the control of Scer\GAL4en-e16E has no effect on germline stem cell number in the female germaria.

      (Guo and Wang, 2009)

      Expression of dallyScer\UAS.cJa under the control of Scer\GAL4en-e16E increases the posterior:anterior size ratio of the appendage-forming region of the haltere disc from the wild-type ratio of 0.48 to 0.59. The overall size of the adult haltere is 5% larger in animals of this genotype than in controls.

      (Crickmore and Mann, 2007)

      Expression of dallyScer\UAS.cJa in the wing, under the control of Scer\GAL4en-e16E, results in enlargement of the posterior portion by 46%, and enlargement of the anterior portion by a more modest 13%. In addition, the formation of the posterior and anterior crossveins are disrupted in these wings.

      Expression of dallyScer\UAS.cJa in the eye, driven by Scer\GAL4ey.PH, causes an eye overgrowth phenotype. Ommatidia in these eyes are misshapen, with a reduced number of photoreceptors per ommatidial unit.

      Expression of dallyScer\UAS.cJa under the control of Scer\GAL4A9 in a dallygem/dallyΔP-527 or dallygem mutant background results in the formation of excess dorsocentral bristles (the excess is around 30% compared to wild-type wings).

      (Kirkpatrick et al., 2006)

      The posterior compartment/anterior compartment width ratio is increased in the haltere pouches of larvae expressing dallyScer\UAS.cJa under the control of Scer\GAL4en-e16E compared to control discs.

      (de Navas et al., 2006)

      Expression of dallyScer\UAS.cJa, under the control of both Scer\GAL4how-24B and Scer\GAL4G14, produces SNa bifurcation phenotypes at a low penetrance (~11%).

      (Fox and Zinn, 2005)

      Expression of dallyScer\UAS.cJa driven by Scer\GAL4en-e16E or Scer\GAL4prd.RG1 produces cuticle defects consistent with an increase in the level of wg activity. High levels of expression are lethal and few embryos survive to produce cuticle.

      (Tsuda et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      NOT Suppressor of
      Other
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Scer\GAL4ey.PH, dallyUAS.cJa has eye photoreceptor cell phenotype, suppressible by Mad[+]/Madunspecified

      (Kirkpatrick et al., 2006)
      Enhancer of
      NOT Enhancer of
      Statement
      Reference

      dallyUAS.cJa/Scer\GAL4C-765 is a non-enhancer of wing disc | larval stage phenotype of fweΔExtra.EGFP

      (Merino et al., 2022)

      dallyUAS.cJa/Scer\GAL4C-765 is a non-enhancer of wing disc | larval stage phenotype of magu2

      (Merino et al., 2022)
      NOT Suppressor of
      Other
      Statement
      Reference

      dallyUAS.cJa, hhMrt has wing | anterior phenotype

      (Jackson et al., 1997)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of dallyScer\UAS.cJa with enokGD4037 and enokHM05195 under the control of Scer\GAL4bab1-Gal4 and Scer\GAL80ts.αTub84B is unable to attenuate the decline in germline stem cell numbers.

      (Xin et al., 2013)

      The reduction in the number of photoreceptors per ommatidia seen in eyes that express dallyScer\UAS.cJa under the control of Scer\GAL4ey.PH is suppressed in a Madunspecified/+ mutant background.

      (Kirkpatrick et al., 2006)

      Potentiates the hhMrt/+ phenotype, converting the wing overgrowth phenotype to mirror image wing duplications in hhMrt/+ ; dallyScer\UAS.cJa flies. This phenotype is seen in the absence of a Scer\GAL4 activator in a number of different P{UAS-dally.J} insertion lines.

      (Jackson et al., 1997)
      Xenogenetic Interactions
      Statement
      Reference

      Expression of dallyScer\UAS.cJa synergistically enhances the wing defects seen when Drer\wif1Scer\UAS.cAa is expressed under the control of Scer\GAL4nub-AC-62. Wing margin bristles and the first longitudinal vein are almost completely eliminated. Wing size is further reduced.

      (Avanesov et al., 2012)
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      dallyScer\UAS.cJa
      dallyUAS.cJa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Jackson
      (Jackson et al., 1997)
      Secondary FlyBase IDs
        References (28)