FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\cncUAS.cVa
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General Information
Symbol
Dmel\cncUAS.cVa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Veraksa
FlyBase ID
FBal0119282
Feature type
allele
Associated gene
Dmel\cnc
Associated Insertion(s)
Carried in Construct
P{UAS-cnc.B}
Also Known As
UAS-CncB
Key Links
Transgenic product class
wild_type
(Veraksa et al., 2000)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Veraksa et al., 2000)
Mutagen
in vitro construct
(Veraksa et al., 2000)
Progenitor genotype
Carried in construct
P{UAS-cnc.B}
Cytology
Description

UASt sequences drive expression of cncB sequences.

(Veraksa et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
cnc
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of cncScer\UAS.cVa in the eye under the control of Scer\GAL4GMR.PF results in ommatidial loss and a smooth eye appearance.

      Overexpression of cncScer\UAS.cVa in the eye under the control of Scer\GAL4sev.EP has no phenotypic effect at 25 [o]C.

      (Sykiotis and Bohmann, 2008)

      When cncScer\UAS.cVa is ubiquitously expressed by Scer\GAL469B, the abdominal denticle pattern along the ventral midline of the embryo is replaced with a band of incurved folds, which resemble the T-ribs of the ventral pharynx.

      (Veraksa et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhanced by
      NOT suppressed by
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Keap1Scer\UAS.cSa under the control of Scer\GAL4GMR.PF does not modify the cncScer\UAS.cVa gain-of-function phenotype in the eye.

      (Sykiotis and Bohmann, 2008)

      The addition of maf-SScer\UAS.cVa has no effect on the pharyngeal phenotype seen in cncScer\UAS.cVa, Scer\GAL469B animals.

      (Veraksa et al., 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL4ppk.PU/cncUAS.cVa fails to rescue cnc1223

      (Chew et al., 2021)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      cncScer\UAS.cVa
      cncUAS.cVa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Veraksa
      (Veraksa et al., 2000)
      Secondary FlyBase IDs
        References (4)