FlyBase Allele Report: Dmel\EP1216b[EP1216b]

General Information

Symbol

Dmel\EP1216b^EP1216b

Species

D. melanogaster

Name

FlyBase ID

FBal0119655

Feature type

allele

Associated gene

EP1216b

Associated Insertion(s)

P{EP}EP1216b^EP1216b

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Wing et al., 2002, Abdelilah-Seyfried et al., 2000, FlyBase, 1996-)

Progenitor genotype

Associated Insertion(s)

P{EP}EP1216b^EP1216b

Cytology

Description

P{EP} insertion at approximately -2.9kb relative to the transcript.

(Abdelilah-Seyfried et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

Phenotype Manifest In

macrochaeta | ectopic, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

tormogen cell, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

trichogen cell, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

trichogen cell | ectopic, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

Detailed Description

Statement

Reference

Expression of EP1216b^EP1216b under the control of Scer\GAL4^sca-537.4 results in additional macrochaetae. Sensory organs with two sockets and two shafts, no socket, one shaft and one sheath cell and small shaft morphology are seen.

(Abdelilah-Seyfried et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

EP1216b^EP1216b, Scer\GAL4^sca-537.4 has visible phenotype, non-enhanceable by H[+]/H^E21

(Abdelilah-Seyfried et al., 2000)

EP1216b^EP1216b, Scer\GAL4^sca-537.4 has visible phenotype, non-enhanceable by N[+]/N^55e11

(Abdelilah-Seyfried et al., 2000)

NOT suppressed by

Statement

Reference

EP1216b^EP1216b, Scer\GAL4^sca-537.4 has visible phenotype, non-suppressible by H[+]/H^E21

(Abdelilah-Seyfried et al., 2000)

EP1216b^EP1216b, Scer\GAL4^sca-537.4 has visible phenotype, non-suppressible by N[+]/N^55e11

(Abdelilah-Seyfried et al., 2000)

Suppressor of

Statement

Reference

SkpA^EP1216a/EP1216b^EP1216b, Scer\GAL4^GMR.PF is a suppressor of visible phenotype of Scer\GAL4^GMR.PF, grim::rpr^rg.UAS

(Wing et al., 2002)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Scer\GAL4^sca-537.4/EP1216b^EP1216b is a non-enhancer of phenotype of N^55e11

(Abdelilah-Seyfried et al., 2000)

Scer\GAL4^sca-537.4/EP1216b^EP1216b is a non-enhancer of phenotype of H^E21

(Abdelilah-Seyfried et al., 2000)

Suppressor of

Statement

Reference

SkpA^EP1216a/EP1216b^EP1216b, Scer\GAL4^GMR.PF is a suppressor of eye phenotype of Scer\GAL4^GMR.PF, grim::rpr^rg.UAS

(Wing et al., 2002)

NOT Suppressor of

Statement

Reference

Scer\GAL4^sca-537.4/EP1216b^EP1216b is a non-suppressor of phenotype of H^E21

(Abdelilah-Seyfried et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

The eye phenotype caused by expression of grim::rpr^rg.Scer\UAS under the control of Scer\GAL4^GMR.PF is suppressed by the "EP1216" line, which contains two P{EP} insertions; P{EP}Suv4-20^EP1216a and P{EP}EP1216b^EP1216b.

(Wing et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Separable from: Suv4-20^EP1216a. Separable from: skpA^EP1216a.

(FlyBase, 1996-)

Separable from: P{EP}Suv4-20^EP1216a.

(Abdelilah-Seyfried et al., 2000)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

EP(X)1216b

(Abdelilah-Seyfried et al., 2000)

EP1216

(Wing et al., 2002)

EP1216b^EP1216b

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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