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General Information
Symbol
Dmel\tkvDN.UAS.cUa
Species
D. melanogaster
Name
FlyBase ID
FBal0120305
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-TkvDN
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS sequences drive expression of a dominant negative tkv.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

When tkvDN.Scer\UAS is driven by Scer\GAL4pnr-MD237, a strong thorax cleft phenotype is seen in the adult. Both hemi-nota remain extremely contracted and isolated. Naked cuticle joins the two heminota. When tkvDN.Scer\UAS is driven by Scer\GAL4LE a milder thorax cleft phenotype is seen in the adult. Cuticular polarity defects are seen at the midline. Occasionally stronger defects are seen.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Phenotype Manifest In
Enhancer of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of tkvDN.Scer\UAS enhances the migration of wing disc cells expressing GliScer\UAS.cSa under the control of Scer\GAL4ap.PU into the non-expressing side of the disc.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
tkvDN.Scer\UAS
tkvDN.UAS.cUa
tkvDN.UAS
Name Synonyms
Secondary FlyBase IDs
    References (7)