FlyBase Allele Report: Dmel\amn[UAS.cWa]

General Information

Symbol

Dmel\amn^UAS.cWa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Waddell

FlyBase ID

FBal0120569

Feature type

allele

Associated gene

Dmel\amn

Associated Insertion(s)

Carried in Construct

P{UAS-amn.W}

Also Known As

uas-amn

Key Links

Transgenic product class

wild_type

(Waddell et al., 2000)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Waddell et al., 2000)

Mutagen

in vitro construct

(Waddell et al., 2000)

Progenitor genotype

Carried in construct

P{UAS-amn.W}

Cytology

Description

Expression of a full length amn ORF is governed by UASt regulatory sequences.

(Waddell et al., 2000)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

amn

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal memory

(Keene et al., 2004)

abnormal memory, with Scer\GAL4^c316, amn^X8

(Keene et al., 2004)

abnormal memory, with Scer\GAL4^Mz717, amn^X8

(Keene et al., 2004)

Phenotype Manifest In

Detailed Description

Statement

Reference

amn^X8;Scer\GAL4^c316/amn^Scer\UAS.cWa and amn^X8;Scer\GAL4^Mz717/amn^Scer\UAS.cWa flies learn to avoid benzaldehyde significantly better than amn^X8 flies, although their performance is still significantly worse than that of wild-type flies. In contrast, OCT immediate memory of amn^X8 flies is indistinguishable from wild-type flies and amn^X8;Scer\GAL4^c316/amn^Scer\UAS.cWa and amn^X8;Scer\GAL4^Mz717/amn^Scer\UAS.cWa flies.

(Keene et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

amn^UAS.cWa/Scer\GAL4^da.G32 rescues amn^X8/amn^28A

(Aldrich et al., 2010)

amn^UAS.cWa/Scer\GAL4^c316 rescues amn^X8/amn¹

(Keene et al., 2006)

amn^UAS.cWa/Scer\GAL4^c316 rescues amn¹

(Keene et al., 2006)

amn^UAS.cWa/Scer\GAL4^c316 rescues amn^X8

(Yu et al., 2005)

amn^UAS.cWa/Scer\GAL4^c316 rescues amn^chpd

(Yu et al., 2005)

amn^UAS.cWa/Scer\GAL4^c316 rescues amn^X8

(Waddell et al., 2000)

Fails to rescue

amn^UAS.cWa/Scer\GAL4^c309 fails to rescue amn^X8

(Waddell et al., 2000)

Scer\GAL4^c747/amn^UAS.cWa fails to rescue amn^X8

(Waddell et al., 2000)

Comments

The presence of amn^Scer\UAS.cWa under the control of Scer\GAL4^da.G32 significantly rescues the delayed larval and adult response to noxious heat in amn^28A/amn^X8 females.

(Aldrich et al., 2010)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

amn^Scer\UAS.cWa

amn^UAS.cWa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Waddell

(Waddell et al., 2000)

Secondary FlyBase IDs

References (7)

Report Sections

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