FlyBase Allele Report: Dmel\nanos[nanos.+1.+2']

General Information

Symbol

Dmel\nanos^nanos.+1.+2'

Species

D. melanogaster

Name

FlyBase ID

FBal0121641

Feature type

allele

Associated gene

Dmel\nanos

Associated Insertion(s)

Carried in Construct

P{nanos-tub:nanos+2(^)}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Bergsten et al., 2001)

Progenitor genotype

nanos^{nanos.+1.Hsp83}

(Bergsten et al., 2001)

Carried in construct

P{nanos-tub:nanos+2(^)}

Cytology

Description

Construct: +2' element sequences from the nos 3' UTR have been inserted downstream of the +1 element within the αTub84B 3' UTR sequences present in nos^nos.+1.Hsp83. As a result, the +1 and +2' sequences are separated by 130bp of αTub84B 3' UTR sequence.

(Bergsten et al., 2001)

Allele components

Component

Use(s)

Encoded product / tool

nanos

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

wild-type

(Bergsten et al., 2001)

Phenotype Manifest In

Detailed Description

Statement

Reference

Embryos derived from nos^BN females which are also expressing nos^nos.+1.+2' do not have anterior defects.

(Bergsten et al., 2001)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

nanos^nanos.+1.+2' is a non-suppressor of embryonic abdominal segment phenotype of vas¹/vas³

(Bergsten et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

nos^nos.+1.+2' fails to rescue the abdominal segmentation defect of embryos derived from vas¹/vas³ females; 100% of the embryos develop no abdominal segments. The embryos do not have anterior defects.

(Bergsten et al., 2001)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

nanos^nanos.+1.+2' rescues nanos^BN

(Bergsten et al., 2001)

Comments

nos^nos.+1.+2' rescues the abdominal segmentation defect of embryos derived from nos^BN females; 6% develop 4-6 abdominal segments and 94% develop 7-8 abdominal segments.

(Bergsten et al., 2001)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

nanos^nanos.+1.+2'

nanos^nos.+1.+2'

nos^nos.+1.+2'

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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