FlyBase Allele Report: Dmel\E(Mer)IIb[187]

General Information

Symbol

Dmel\E(Mer)IIb¹⁸⁷

Species

D. melanogaster

Name

FlyBase ID

FBal0124260

Feature type

allele

Associated gene

E(Mer)IIb

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(LaJeunesse et al., 2001)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of larval stage | recessive

(LaJeunesse et al., 2001)

some die during larval stage | recessive

(LaJeunesse et al., 2001)

visible (with Df(2L)Mdh)

(LaJeunesse et al., 2001)

Phenotype Manifest In

wing vein | ectopic (with Df(2L)Mdh)

(LaJeunesse et al., 2001)

Detailed Description

Statement

Reference

Lethal in combination with other alleles of E(Mer)IIb (transheterozygotes die as early larvae with no distinct phenotypes). E(Mer)IIb¹⁸⁷/Df(2L)Mdh flies have extra wing vein material.

(LaJeunesse et al., 2001)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

E(Mer)IIb¹⁸⁷ is an enhancer of partially lethal | recessive | male phenotype of Mer³

(LaJeunesse et al., 2001)

E(Mer)IIb¹⁸⁷ is an enhancer of visible phenotype of Mer^{ΔBB.UAS.Tag:MYC}, Scer\GAL4^en-e16E

(LaJeunesse et al., 2001)

Other

Statement

Reference

E(Mer)IIb¹⁸⁷, Mer^{ΔBB.UAS.Tag:MYC}, Scer\GAL4^ap-md52 has visible phenotype

(LaJeunesse et al., 2001)

E(Mer)IIb¹⁸⁷, Mer^{ΔBB.UAS.Tag:MYC}, Scer\GAL4^en-e16E has visible phenotype

(LaJeunesse et al., 2001)

Phenotype Manifest In

Enhanced by

Statement

Reference

E(Mer)IIb¹⁸⁷ has wing disc posterior compartment phenotype, enhanceable by Scer\GAL4^en-e16E/Mer^{ΔBB.UAS.Tag:MYC}

(LaJeunesse et al., 2001)

Enhancer of

Statement

Reference

E(Mer)IIb¹⁸⁷ is an enhancer of anterior crossvein phenotype of Mer^{ΔBB.UAS.Tag:MYC}, Scer\GAL4^en-e16E

(LaJeunesse et al., 2001)

E(Mer)IIb¹⁸⁷ is an enhancer of posterior crossvein phenotype of Mer^{ΔBB.UAS.Tag:MYC}, Scer\GAL4^en-e16E

(LaJeunesse et al., 2001)

E(Mer)IIb¹⁸⁷ is an enhancer of wing vein | ectopic phenotype of Mer^{ΔBB.UAS.Tag:MYC}, Scer\GAL4^en-e16E

(LaJeunesse et al., 2001)

Other

Statement

Reference

E(Mer)IIb¹⁸⁷, Mer^{ΔBB.UAS.Tag:MYC}, Scer\GAL4^ap-md52 has wing phenotype

(LaJeunesse et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Allele strength (based on interactions with Mer^{ΔBB.Scer\UAS.T:Hsap\MYC}, Scer\GAL4^en-e16E): E(Mer)IIb¹⁸⁷, E(Mer)IIb¹⁸² > E(Mer)IIb²⁰⁹.

(LaJeunesse et al., 2001)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

E(Mer)IIb¹⁸⁷

IIb¹⁸⁷

(LaJeunesse et al., 2001)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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