FlyBase Allele Report: Dmel\Drep2[KG02396]

General Information

Symbol

Dmel\Drep2^KG02396

Species

D. melanogaster

Name

FlyBase ID

FBal0130796

Feature type

allele

Associated gene

Dmel\Drep2

Associated Insertion(s)

P{SUPor-P}Drep2^KG02396

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{SUPor-P}Drep2^KG02396

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{SUPor-P}

insertional mutagenesis tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:9,292,661..9,292,661 [-]

(Tan et al., 2012, Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates neurodegenerative disease

modeled by Zzzz\CGG^90.UAS.EGFP

(Tan et al., 2012)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Heterozygous Drep-2^KG02396 has no effect on eye morphology.

(Tan et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Drep-2[+]/Drep2^KG02396 is an enhancer of visible | adult stage phenotype of Scer\GAL4^GMR.PF, Zzzz\CGG^90.UAS.EGFP

(Tan et al., 2012)

Drep-2[+]/Drep2^KG02396 is an enhancer of abnormal neuroanatomy | adult stage phenotype of Scer\GAL4^GMR.PF, Zzzz\CGG^90.UAS.EGFP

(Tan et al., 2012)

Phenotype Manifest In

Enhancer of

Statement

Reference

Drep-2[+]/Drep2^KG02396 is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, Zzzz\CGG^90.UAS.EGFP

(Tan et al., 2012)

Drep-2[+]/Drep2^KG02396 is an enhancer of ommatidium phenotype of Scer\GAL4^GMR.PF, Zzzz\CGG^90.UAS.EGFP

(Tan et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

One copy of Drep-2^KG02396 enhances the fused ommatidia phenotype seen when Avic\GFP^{Fmr1.CGG90.E.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PF.

(Tan et al., 2012)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

13312

y¹ w^67c23; P{SUPor-P}Drep2^KG02396

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Drep-2^KG02396

(Tan et al., 2012)

Drep2^KG02396

Drep2^LOF

(Tan et al., 2012)

Rep2^KG02396

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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