FB2026_02 , released June 18, 2026
Allele: Dmel\CthKG02526
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General Information
Symbol
Dmel\CthKG02526
Species
D. melanogaster
Name
FlyBase ID
FBal0134242
Feature type
allele
Associated gene
Dmel\Cth
Associated Insertion(s)
P{SUPor-P}CthKG02526
Carried in Construct
Also Known As
Eip55EKG02526
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{SUPor-P}CthKG02526
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{SUPor-P}
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  Parkinson's disease
      modeled by Hsap\SNCAUAS.cTa
      (Trinh et al., 2008)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eip55EKG02526 mutants do not exhibit detectable neuron loss in 20-day old flies.

      Glutathione abundance is decreased by approximately one-third in Eip55EKG02526 homozygotes, relative to controls.

      (Trinh et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      CthKG02526/Eip55E[+] is a non-suppressor of lethal phenotype of ari-13747

      (Gradilla et al., 2011)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      The loss of DA neurons caused by Hsap\SNCAScer\UAS.cTa expression in 20-day old adults is enhanced by a Eip55EKG02526 background.

      (Trinh et al., 2008)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CthKG02526
      Eip55EKG02526
      (Gradilla et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)