FlyBase Allele Report: Dmel\prd[mf9]

General Information

Symbol

Dmel\prd^mf9

Species

D. melanogaster

Name

FlyBase ID

FBal0135638

Feature type

allele

Associated gene

Dmel\prd

Associated Insertion(s)

Carried in Construct

P{prd-mf9.GAL4}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Xue and Noll, 2002)

Progenitor genotype

prd^mf7

(Xue and Noll, 2002)

Carried in construct

P{prd-mf9.GAL4}

Cytology

Description

A 1kb fragment downstream of the prd male fertility enhancer (PMFE) has been deleted.

(Xue and Noll, 2002)

Allele components

Component

Use(s)

Regulatory region(s)

prd_PMFE

Encoded product / tool

prd

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

wild-type

(Xue and Noll, 2002)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Df(2L)Prl/prd⁴, prd^mf9 has male sterile phenotype, suppressible by Scer\GAL4^mf9/CycE^UAS.cLa

(Xue and Noll, 2002)

Df(2L)Prl/prd⁴, prd^mf9 has male sterile phenotype, suppressible by Myc^UAS.cZa/Scer\GAL4^mf9

(Xue and Noll, 2002)

NOT suppressed by

Statement

Reference

Df(2L)Prl/prd⁴, prd^mf9 has male sterile phenotype, non-suppressible by Df(3L)th102

(Xue and Noll, 2002)

Df(2L)Prl/prd⁴, prd^mf9 has male sterile phenotype, non-suppressible by Df(3L)H99

(Xue and Noll, 2002)

Df(2L)Prl/prd⁴, prd^mf9 has male sterile phenotype, non-suppressible by Scer\GAL4^mf9/Pi3K92E^UAS.Tag:MYC

(Xue and Noll, 2002)

Df(2L)Prl, prd⁴, prd^mf9 has male sterile phenotype, non-suppressible by Df(3L)th102

(Xue and Noll, 2002)

Df(2L)Prl, prd⁴, prd^mf9 has male sterile phenotype, non-suppressible by Df(3L)H99

(Xue and Noll, 2002)

Df(2L)Prl, prd⁴, prd^mf9 has male sterile phenotype, non-suppressible by Scer\GAL4^mf9/Pi3K92E^UAS.Tag:MYC

(Xue and Noll, 2002)

Phenotype Manifest In

Suppressed by

Statement

Reference

Df(2L)Prl/prd⁴, prd^mf9 has male accessory gland phenotype, suppressible by Scer\GAL4^mf9/CycE^UAS.cLa

(Xue and Noll, 2002)

Df(2L)Prl/prd⁴, prd^mf9 has male accessory gland phenotype, suppressible by Myc^UAS.cZa/Scer\GAL4^mf9

(Xue and Noll, 2002)

NOT suppressed by

Statement

Reference

Df(2L)Prl/prd⁴, prd^mf9 has male accessory gland phenotype, non-suppressible by Scer\GAL4^mf9/BacA\p35^UAS.cHa

(Xue and Noll, 2002)

Df(2L)Prl, prd⁴, prd^mf9 has male accessory gland phenotype, non-suppressible by Df(3L)th102

(Xue and Noll, 2002)

Df(2L)Prl, prd⁴, prd^mf9 has male accessory gland phenotype, non-suppressible by Df(3L)H99

(Xue and Noll, 2002)

Df(2L)Prl, prd⁴, prd^mf9 has male accessory gland phenotype, non-suppressible by Scer\GAL4^mf9/Pi3K92E^UAS.Tag:MYC

(Xue and Noll, 2002)

Df(2L)Prl/prd⁴, prd^mf9 has male accessory gland phenotype, non-suppressible by Df(3L)th102

(Xue and Noll, 2002)

Df(2L)Prl/prd⁴, prd^mf9 has male accessory gland phenotype, non-suppressible by Df(3L)H99

(Xue and Noll, 2002)

Df(2L)Prl/prd⁴, prd^mf9 has male accessory gland phenotype, non-suppressible by Scer\GAL4^mf9/Pi3K92E^UAS.Tag:MYC

(Xue and Noll, 2002)

Additional Comments

Genetic Interactions

Statement

Reference

When CycE^Scer\UAS.cLa or dm^Scer\UAS.cZa (driven by Scer\GAL4^mf9) is added to Df(2L)Prl/prd⁴, (partially rescued by a weakly expressing prd^mf9 line), the accessory gland phenotype is reduced, and male fertility is restored. When Df(3L)H99, Df(3L)th102 or Pi3K92E^{Scer\UAS.T:Hsap\MYC} is added to Df(2L)Prl/prd⁴ animals (already partially suppressed by the addition of prd^mf9) no suppression is seen in the accessory gland or make sterility phenotypes.

(Xue and Noll, 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

prd^mf9 rescues Df(2L)Prl/prd⁴

(Xue and Noll, 2002)

prd^UAS.cJa, prd^mf9, Scer\GAL4^mf9 rescues Df(2L)Prl/prd⁴

(Xue and Noll, 2002)

Comments

One copy of prd^mf9 can partially rescues the prd⁴/Df(2L)Prl accessory gland phenotype, two copies fully rescues.

(Xue and Noll, 2002)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

prd^mf9

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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