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General Information
Symbol
Dmel\htsKG06777
Species
D. melanogaster
Name
FlyBase ID
FBal0137227
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{SUPor-P}htsKG06777
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

centrosome & spermatocyte (with Df(2R)BSC26)

fusome & testis (with Df(2R)BSC26)

germ cell & egg chamber (with Df(2R)BSC26)

spindle & spermatocyte (with Df(2R)BSC26)

Detailed Description
Statement
Reference

Many egg chambers from htsKG06777/Df(2R)BSC26 frequently lack a full complement of germ cells.

Gonial cells of htsKG06777/Df(2R)BSC26 testes rarely show branched fusome structures by immunostaining of Klp61F, although open ring structures (that probably correspond to the lumen of forming ring canals) are detected.

In contrast to wild type, many spermatocytes in htsKG06777/Df(2R)BSC26 mutants contain too many or too few centrosomes.

In contrast to wild type, 19% of meiotic spermatocytes in htsKG06777/Df(2R)BSC26 mutant testes show spindle abnormalities, including monopolar and multipolar spindles.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
Phenotype Manifest In
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments

Based on fusome assembly and immunoblot analysis, hts mutants can be placed in an allelic series from the most to the least severe: hts01103 > hts1 > htsKG06777 > htsk06121.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (3)