FlyBase Allele Report: Scer\GAL4[eve.eme]

General Information

Symbol

Scer\GAL4^eve.eme

Species

S. cerevisiae

Name

FlyBase ID

FBal0141435

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{eve-GAL4.eme}

Also Known As

eme-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Han et al., 2002)

Progenitor genotype

Carried in construct

P{eve-GAL4.eme}

Cytology

Description

Two copies of the eve mesoderm enhancer (+5.8 to +6.6 kb) lie upstream of the eve promoter (nt -275 to +11), followed by polylinker sequences and the eve 5' untranslated leader (+91 to +9nt). This is fused with the GAL4 coding region (resulting in the replacement of the yeast initiation site being replaced by that from eve), and followed by the eve 3' untranslated region (+1306 to +1521 nt).

(Han et al., 2002)

Allele components

Component

Use(s)

Regulatory region(s)

eve

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 15

muscle cell of dorsal acute muscle 1

(Bataillé et al., 2010)

abdominal dorsal transverse muscle 1 founder cell

(Bataillé et al., 2010)

muscle cell of dorsal oblique muscle 1

(Bataillé et al., 2010)

muscle cell of dorsal oblique muscle 2

(Bataillé et al., 2010)

Additional Information

Statement

Reference

Marker for

Reflects expression of

eve

(Bataillé et al., 2010)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

dorsal transverse muscle cell, with Pax^UAS.cCa

(Bataillé et al., 2010)

dorsal vessel wall cell, with sli^UAS.cBa

(Qian et al., 2005)

embryonic pericardial cell, with dap^UAS.cLa

(Han and Bodmer, 2003)

embryonic pericardial cell, with numb^{fl.UAS.Tag:MYC}

(Han and Bodmer, 2003)

muscle cell of A1-7 dorsal acute muscle 1, with N^int.G.UAS

(Han and Bodmer, 2003)

muscle cell of A1-7 dorsal acute muscle 1, with Su(H)^VP16.UAS

(Han and Bodmer, 2003)

muscle cell of A1-7 dorsal oblique muscle 2, with N^int.G.UAS

(Han and Bodmer, 2003)

muscle cell of dorsal acute muscle 1, with Mp20^UAS.cBa

(Bataillé et al., 2010)

muscle cell of dorsal acute muscle 1, with mspo^UAS.cUa

(Bataillé et al., 2010)

muscle cell of dorsal acute muscle 1, with Pax^UAS.cCa

(Bataillé et al., 2010)

muscle cell of mesothoracic dorsal acute muscle 1, with N^int.G.UAS

(Han and Bodmer, 2003)

muscle cell of mesothoracic dorsal acute muscle 1, with Su(H)^VP16.UAS

(Han and Bodmer, 2003)

muscle cell of mesothoracic dorsal oblique muscle 2, with N^int.G.UAS

(Han and Bodmer, 2003)

muscle cell of metathoracic dorsal acute muscle 1, with N^int.G.UAS

(Han and Bodmer, 2003)

muscle cell of metathoracic dorsal acute muscle 1, with Su(H)^VP16.UAS

(Han and Bodmer, 2003)

muscle cell of metathoracic dorsal oblique muscle 2, with N^int.G.UAS

(Han and Bodmer, 2003)

muscle cell of prothoracic dorsal oblique muscle 2, with N^int.G.UAS

(Han and Bodmer, 2003)

muscle cell of ventral transverse muscle 1, with Pax^UAS.cCa

(Bataillé et al., 2010)

nucleus, with mspo^UAS.cUa

(Bataillé et al., 2010)

nucleus | increased number, with Mp20^UAS.cBa

(Bataillé et al., 2010)

nucleus | increased number, with Pax^UAS.cCa

(Bataillé et al., 2010)

pericardial cell, with Su(H)^VP16.UAS

(Han and Bodmer, 2003)

pericardial cell | ectopic, with N^int.G.UAS

(Han and Bodmer, 2003)

pericardial cell | ectopic, with Su(H)^VP16.UAS

(Han and Bodmer, 2003)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Mp20^UAS.cBa, Scer\GAL4^eve.eme has muscle cell of dorsal acute muscle 1 phenotype, enhanceable by Pax^UAS.cCa, Scer\GAL4^eve.eme

(Bataillé et al., 2010)

Mp20^UAS.cBa, Scer\GAL4^eve.eme has nucleus | increased number phenotype, enhanceable by Pax^UAS.cCa, Scer\GAL4^eve.eme

(Bataillé et al., 2010)

Suppressed by

Statement

Reference

Scer\GAL4^eve.eme, mspo^UAS.cUa has muscle cell of dorsal acute muscle 1 phenotype, suppressible by Mp20^UAS.cBa, Scer\GAL4^eve.eme

(Bataillé et al., 2010)

Scer\GAL4^eve.eme, mspo^UAS.cUa has nucleus phenotype, suppressible by Mp20^UAS.cBa, Scer\GAL4^eve.eme

(Bataillé et al., 2010)

Scer\GAL4^eve.eme, mspo^UAS.cUa has muscle cell of dorsal acute muscle 1 phenotype, suppressible by Pax^UAS.cCa, Scer\GAL4^eve.eme

(Bataillé et al., 2010)

Scer\GAL4^eve.eme, mspo^UAS.cUa has nucleus phenotype, suppressible by Pax^UAS.cCa, Scer\GAL4^eve.eme

(Bataillé et al., 2010)

N^int.G.UAS, Scer\GAL4^eve.eme has muscle cell of mesothoracic dorsal acute muscle 1 phenotype, suppressible | partially by numb^{fl.UAS.Tag:MYC}, Scer\GAL4^eve.eme

(Han and Bodmer, 2003)

N^int.G.UAS, Scer\GAL4^eve.eme has muscle cell of metathoracic dorsal acute muscle 1 phenotype, suppressible | partially by numb^{fl.UAS.Tag:MYC}, Scer\GAL4^eve.eme

(Han and Bodmer, 2003)

N^int.G.UAS, Scer\GAL4^eve.eme has pericardial cell | ectopic phenotype, suppressible | partially by numb^{fl.UAS.Tag:MYC}, Scer\GAL4^eve.eme

(Han and Bodmer, 2003)

N^int.G.UAS, Scer\GAL4^eve.eme has muscle cell of A1-7 dorsal acute muscle 1 phenotype, suppressible | partially by numb^{fl.UAS.Tag:MYC}, Scer\GAL4^eve.eme

(Han and Bodmer, 2003)

Enhancer of

Statement

Reference

Pax^UAS.cCa, Scer\GAL4^eve.eme is an enhancer of muscle cell of dorsal acute muscle 1 phenotype of Mp20^UAS.cBa, Scer\GAL4^eve.eme

(Bataillé et al., 2010)

Pax^UAS.cCa, Scer\GAL4^eve.eme is an enhancer of nucleus | increased number phenotype of Mp20^UAS.cBa, Scer\GAL4^eve.eme

(Bataillé et al., 2010)

Suppressor of

Statement

Reference

Mp20^UAS.cBa, Scer\GAL4^eve.eme is a suppressor of muscle cell of dorsal acute muscle 1 phenotype of Scer\GAL4^eve.eme, mspo^UAS.cUa

(Bataillé et al., 2010)

Mp20^UAS.cBa, Scer\GAL4^eve.eme is a suppressor of nucleus phenotype of Scer\GAL4^eve.eme, mspo^UAS.cUa

(Bataillé et al., 2010)

Pax^UAS.cCa, Scer\GAL4^eve.eme is a suppressor of muscle cell of dorsal acute muscle 1 phenotype of Scer\GAL4^eve.eme, mspo^UAS.cUa

(Bataillé et al., 2010)

Pax^UAS.cCa, Scer\GAL4^eve.eme is a suppressor of nucleus phenotype of Scer\GAL4^eve.eme, mspo^UAS.cUa

(Bataillé et al., 2010)

eve^UAS.cBa/Scer\GAL4^eve.eme is a suppressor of adult heart muscle cell phenotype of lbe^eve.SS

(Buechling et al., 2009)

eve^UAS.cBa/Scer\GAL4^eve.eme is a suppressor of larval pericardial cell | larval stage phenotype of lbe^eve.SS

(Buechling et al., 2009)

eve^UAS.cBa/Scer\GAL4^eve.eme is a suppressor of adult heart phenotype of lbe^eve.SS

(Buechling et al., 2009)

numb^{fl.UAS.Tag:MYC}, Scer\GAL4^eve.eme is a suppressor | partially of muscle cell of mesothoracic dorsal acute muscle 1 phenotype of N^int.G.UAS, Scer\GAL4^eve.eme

(Han and Bodmer, 2003)

numb^{fl.UAS.Tag:MYC}, Scer\GAL4^eve.eme is a suppressor | partially of muscle cell of metathoracic dorsal acute muscle 1 phenotype of N^int.G.UAS, Scer\GAL4^eve.eme

(Han and Bodmer, 2003)

numb^{fl.UAS.Tag:MYC}, Scer\GAL4^eve.eme is a suppressor | partially of pericardial cell | ectopic phenotype of N^int.G.UAS, Scer\GAL4^eve.eme

(Han and Bodmer, 2003)

numb^{fl.UAS.Tag:MYC}, Scer\GAL4^eve.eme is a suppressor | partially of muscle cell of A1-7 dorsal acute muscle 1 phenotype of N^int.G.UAS, Scer\GAL4^eve.eme

(Han and Bodmer, 2003)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

lbe^GD4157/Scer\GAL4^eve.eme rescues lbe^eve.SS

(Buechling et al., 2009)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^eve.eme

Name Synonyms

Secondary FlyBase IDs

References (9)

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